{ "dataset": { "name": "Clinical Trial Tracker: Metabolic & Aesthetic Medicine", "url": "https://nphla.com/trackers/clinical-trial-tracker", "description": "Clinical trials followed in metabolic and aesthetic medicine — obesity and incretin therapies, neurotoxins, dermal fillers, regenerative treatments and hair restoration — with each study’s status, phase and latest registry update.", "publisher": "National Pharmacy Health & Leadership Alliance", "howToCite": "National Pharmacy Health & Leadership Alliance (NPHLA). nphla.com. “Clinical Trial Tracker: Metabolic & Aesthetic Medicine.” Updated Nov 15, 2026. https://nphla.com/trackers/clinical-trial-tracker. Accessed November 15, 2026.", "kind": "Clinical trials (ClinicalTrials.gov)", "dataOrigin": "NPHLA analysis of public data", "jurisdiction": "International / multiple", "methodology": "The Intelligence pipeline queries the ClinicalTrials.gov API (version 2) for two broad searches — obesity and incretin therapies, and aesthetic and regenerative medicine (botulinum toxin, dermal fillers, polynucleotides, exosomes, platelet-rich plasma) — and for every topic with a trial query, on the schedule set in the Source Registry. Each study is stored with its registry fields as published. Changes in overall status and newly posted results are recorded with the date the pipeline detected them.\n\nThis tracker lists every tracked study whose last registry update falls within the past 365 days, newest first. Nothing in the table is edited by hand.", "coverage": "Studies on ClinicalTrials.gov — from the United States and other countries — that match the configured searches, from the date tracking began. Studies registered elsewhere, described with other terms, or not updated in the last year are not included.", "limitations": "Registry data is supplied by sponsors and may be incomplete or out of date. Inclusion reflects search terms, not clinical importance. Every therapy in a trial is investigational for the use being studied. Not medical advice.", "updateFrequency": "Registry searches run every 6 to 12 hours, as configured in the Source Registry.", "selection": "ClinicalTrials.gov studies followed by Trial Watch dated within the last 365 days.", "systemCheckedAt": "2026-11-15T17:35:05.565Z", "editoriallyReviewedAt": null, "editorialReview": "pending", "generatedAt": "2026-11-15T20:57:47.762Z", "recordCount": 300, "notAdvice": "Professional information compiled from public sources. Not medical, legal or regulatory advice; always confirm in the primary source." }, "columns": [ { "key": "phase", "label": "Phase" }, { "key": "sponsor", "label": "Sponsor" } ], "records": [ { "key": "trial:NCT07407348", "record": "A Study in People With Overweight or Obesity to Compare How 2 Different Formulations of Survodutide Are Taken up by the Body", "subtitle": "NCT07407348", "detail": "Conditions: Healthy; Obesity; Overweight. Interventions: Formulation A; Formulation B6", "status": "Active, not recruiting", "fields": { "phase": "Phase 1", "sponsor": "Boehringer Ingelheim", "enrollment": "80", "nctId": "NCT07407348" }, "jurisdiction": null, "date": "2026-11-13T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07407348", "url": "https://clinicaltrials.gov/study/NCT07407348", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:04.161Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07935200", "record": "Safety and Pharmacokinetics of UI112 Compared With UIC202611 in Healthy Adults", "subtitle": "NCT07935200", "detail": "Conditions: Bioequivalence; Pharmacokinetics. Interventions: Semaglutide (UI112); Semaglutide (UIC202611)", "status": "Not yet recruiting", "fields": { "phase": "Phase 1", "sponsor": "Korea United Pharm. Inc.", "enrollment": "44", "nctId": "NCT07935200" }, "jurisdiction": null, "date": "2026-11-13T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07935200", "url": "https://clinicaltrials.gov/study/NCT07935200", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:09.947Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:10.023Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07936058", "record": "A Phase I Study to Evaluate the Food Effect on Ecnoglutide Tablet", "subtitle": "NCT07936058", "detail": "Conditions: Food Effect in Healthy Volunteers; Weight Management. Interventions: Dose 1; Dose 2", "status": "Not yet recruiting", "fields": { "phase": "Phase 1", "sponsor": "Hangzhou Sciwind Biosciences Co., Ltd.", "enrollment": "72", "nctId": "NCT07936058" }, "jurisdiction": null, "date": "2026-11-13T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07936058", "url": "https://clinicaltrials.gov/study/NCT07936058", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:04.279Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07936838", "record": "Effects of a Gut-Active Peptide That Stimulates GLP-1 Release on Appetite and Satiety in Healthy Adults With Overweight", "subtitle": "NCT07936838", "detail": "Conditions: Appetite and Hunger, Suppression; Satiety and Appetite; Weight Change; Gastrointestinal Symptoms; Body Composition. Interventions: Lembas Edge™; Placebo", "status": "Not yet recruiting", "fields": { "phase": "Not applicable", "sponsor": "Lembas", "enrollment": "150", "nctId": "NCT07936838" }, "jurisdiction": null, "date": "2026-11-13T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07936838", "url": "https://clinicaltrials.gov/study/NCT07936838", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:04.210Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06716216", "record": "A Study of BGM0504 in Participants With Type 2 Diabetes", "subtitle": "NCT06716216", "detail": "Conditions: Type 2 Diabetes Mellitus (T2DM). Interventions: Drug: 5 mg BGM0504 Administered SC; Drug:10 mg BGM0504 Administered SC; Drug: Semaglutide Administered SC", "status": "Completed", "fields": { "phase": "Phase 3", "sponsor": "BrightGene Bio-Medical Technology Co., Ltd.", "enrollment": "553", "nctId": "NCT06716216" }, "jurisdiction": null, "date": "2026-11-13T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06716216", "url": "https://clinicaltrials.gov/study/NCT06716216", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:09.947Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:09.965Z", "change": { "note": "Status changed from “Active, not recruiting” to “Completed”", "at": "2026-11-13T19:05:09.795Z", "withinLast7Days": true }, "origin": "automated" }, { "key": "trial:NCT06297603", "record": "Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)", "subtitle": "NCT06297603", "detail": "Conditions: Type 2 Diabetes. Interventions: Retatrutide; Placebo", "status": "Active, not recruiting", "fields": { "phase": "Phase 3", "sponsor": "Eli Lilly and Company", "enrollment": "320", "nctId": "NCT06297603" }, "jurisdiction": null, "date": "2026-11-13T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06297603", "url": "https://clinicaltrials.gov/study/NCT06297603", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:07.948Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:07.965Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07931573", "record": "AMBITION 3: AMBITION 3: A Research Study Investigating How Well Zenagamtide at Higher Dose Levels Lowers Blood Sugar and Body Weight Compared to Semaglutide in People With Type 2 Diabetes Treated With Metformin, SGLT2i, or Both", "subtitle": "NCT07931573", "detail": "Conditions: Type 2 Diabetes. Interventions: Zenagamtide; Semaglutide; Placebo", "status": "Not yet recruiting", "fields": { "phase": "Phase 3", "sponsor": "Novo Nordisk A/S", "enrollment": "1200", "nctId": "NCT07931573" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07931573", "url": "https://clinicaltrials.gov/study/NCT07931573", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:09.947Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:10.307Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07931599", "record": "AMBITION4: A Research Study Investigating How Well Zenagamtide at Lower Dose Levels Lowers Blood Sugar and Body Weight Compared to Semaglutide at Lower Dose Levels in People With Type 2 Diabetes Treated With Metformin, Sodium-Glucose Cotransporter 2 Inhibitors (SGLT2i), or Both", "subtitle": "NCT07931599", "detail": "Conditions: Diabetes Mellitus, Type 2. Interventions: Zenagamtide; Semaglutide; Placebo zenagamtide; Placebo semaglutide", "status": "Not yet recruiting", "fields": { "phase": "Phase 3", "sponsor": "Novo Nordisk A/S", "enrollment": "1060", "nctId": "NCT07931599" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07931599", "url": "https://clinicaltrials.gov/study/NCT07931599", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:09.947Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:10.223Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07932119", "record": "GLP-1 Receptor Agonists in the Surgical Patient: Prevalence, Epidemiology, and Pulmonary Complications", "subtitle": "NCT07932119", "detail": "Conditions: GLP-1 Receptor Agonist Treatment. Interventions: GLP-1 Receptor Agonists; GLP-1 Receptor Agonists", "status": "Completed", "fields": { "phase": "Phase not stated", "sponsor": "University of Virginia", "enrollment": "25505", "nctId": "NCT07932119" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07932119", "url": "https://clinicaltrials.gov/study/NCT07932119", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:09.947Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:10.069Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07481747", "record": "SURMOUNT-1: Efficacy and Safety of Tirzepatide Once Weekly Versus Placebo in Participants Who Are Either Obese or Overweight With Weight-Related Comorbidities (SURMOUNT-1)", "subtitle": "NCT07481747", "detail": "Conditions: Obesity; Overweight (Without Type 2 Diabetes) With Weight-related Comorbidities. Interventions: Tirzepatide; Placebo; Reduced-calorie diet", "status": "Recruiting", "fields": { "phase": "Phase 3", "sponsor": "Hudson Biotech", "enrollment": "2539", "nctId": "NCT07481747" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07481747", "url": "https://clinicaltrials.gov/study/NCT07481747", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:08.933Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:09.237Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07931859", "record": "A Retrospective Study to Assess Patient-Reported Treatment Experience With Over-the-Counter Analgesic Products", "subtitle": "NCT07931859", "detail": "Conditions: Pain. Interventions: Paracetamol", "status": "Not yet recruiting", "fields": { "phase": "Phase not stated", "sponsor": "HALEON", "enrollment": "600", "nctId": "NCT07931859" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07931859", "url": "https://clinicaltrials.gov/study/NCT07931859", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:04.932Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07933393", "record": "PRESERVE GLP-1: Lifestyle Strategies to Preserve Muscle and Reduce Cardiovascular Risk in Adults With Obesity Using GLP-1 Receptor Agonists", "subtitle": "NCT07933393", "detail": "Conditions: Obesity & Overweight. Interventions: GLP-1 Lifestyle Management Program; Enhanced Usual Care Health Education", "status": "Not yet recruiting", "fields": { "phase": "Not applicable", "sponsor": "University of Florida", "enrollment": "670", "nctId": "NCT07933393" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07933393", "url": "https://clinicaltrials.gov/study/NCT07933393", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:05.519Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06299098", "record": "COURAGE: A Study to Test if Trevogrumab or Trevogrumab With Garetosmab When Taken With Semaglutide is Safe and How Well They Work in Adult Patients With Obesity for Weight Loss, Fat Loss, and Lean Mass Preservation", "subtitle": "NCT06299098", "detail": "Conditions: Obesity. Interventions: Trevogrumab-Part A; Trevogrumab-Part B and Part C; Garetosmab; Semaglutide; Matching Placebo-Part A; Matching Placebo-T…", "status": "Completed", "fields": { "phase": "Phase 2", "sponsor": "Regeneron Pharmaceuticals", "enrollment": "1005", "nctId": "NCT06299098" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06299098", "url": "https://clinicaltrials.gov/study/NCT06299098", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:09.947Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:10.346Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07931560", "record": "Changes in Body Composition and Muscle Composition After GLP-1 Receptor Agonist Therapy in Patients With Obesity", "subtitle": "NCT07931560", "detail": "Conditions: Obesity & Overweight", "status": "Not yet recruiting", "fields": { "phase": "Phase not stated", "sponsor": "Ulsan University Hospital", "enrollment": "240", "nctId": "NCT07931560" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07931560", "url": "https://clinicaltrials.gov/study/NCT07931560", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:04.728Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07711288", "record": "A Two-part Study of Lembas Edge Evaluating Tolerability and Postprandial Glycemic Control", "subtitle": "NCT07711288", "detail": "Conditions: Postprandial Glycemic Control; Prediabetic Overweight and Obese Adults. Interventions: Low dose alpha-galactosidase-derived peptide; Medium dose alpha-galactosidase-derived peptide; High dose alpha-galactos…", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "Lembas", "enrollment": "35", "nctId": "NCT07711288" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07711288", "url": "https://clinicaltrials.gov/study/NCT07711288", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-13T13:35:06.920Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-13T13:35:07.761Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07932925", "record": "The Purpose of This Study is to Learn About the Safety and Effectiveness of Berobenatide in Women With Urine Leakage and With Obesity or Overweight", "subtitle": "NCT07932925", "detail": "Conditions: Urinary Incontinence, Stress; Overweight and/or Obesity. Interventions: Berobenatide; Placebo", "status": "Not yet recruiting", "fields": { "phase": "Phase 3", "sponsor": "Pfizer", "enrollment": "900", "nctId": "NCT07932925" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07932925", "url": "https://clinicaltrials.gov/study/NCT07932925", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:05.410Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06745284", "record": "A Study to Test Whether Survodutide Improves How the Body Uses Energy and Breaks Down Fat in People With Obesity", "subtitle": "NCT06745284", "detail": "Conditions: Obesity. Interventions: Survodutide; Semaglutide", "status": "Active, not recruiting", "fields": { "phase": "Phase 1", "sponsor": "Boehringer Ingelheim", "enrollment": "64", "nctId": "NCT06745284" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06745284", "url": "https://clinicaltrials.gov/study/NCT06745284", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:04.607Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07540949", "record": "Rutazyme Lemon Fermented Product Capsules for Metabolic Function in Adults With Obesity", "subtitle": "NCT07540949", "detail": "Conditions: Obesity; Metabolic Syndrome. Interventions: Rutazyme® Lemon Fermented Product Capsule; Placebo Capsule (Maltodextrin; GLUCIDEX®12)", "status": "Completed", "fields": { "phase": "Not applicable", "sponsor": "National Taiwan Sport University", "enrollment": "40", "nctId": "NCT07540949" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07540949", "url": "https://clinicaltrials.gov/study/NCT07540949", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:05.465Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06895018", "record": "PoLiFat: Medium-term Effects of a Polyphenol-rich Beverage Based on Red Grape Pomace Extract on Non-alcoholic Fatty Liver Disease, Cardiometabolic Risk Profile and Gut Microbiota in Subjects With Type 2 Diabetes", "subtitle": "NCT06895018", "detail": "Conditions: Diabetes Mellitus Type 2. Interventions: Supplementation with Polyphenol Rich Drink; Supplementation with Control Drink (Placebo)", "status": "Completed", "fields": { "phase": "Not applicable", "sponsor": "Federico II University", "enrollment": "20", "nctId": "NCT06895018" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06895018", "url": "https://clinicaltrials.gov/study/NCT06895018", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:04.438Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07642635", "record": "Glucagon-Like Peptide-1 Receptor Agonists to Attenuate Metabolic Risk in Individuals With Duchenne Muscular Dystrophy", "subtitle": "NCT07642635", "detail": "Conditions: Duchenne Muscular Dystrophy (DMD). Interventions: Semaglutide (Rybelsus®); Placebo", "status": "Recruiting", "fields": { "phase": "Phase 1 / Phase 2", "sponsor": "Vanderbilt University Medical Center", "enrollment": "30", "nctId": "NCT07642635" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07642635", "url": "https://clinicaltrials.gov/study/NCT07642635", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:04.670Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07932977", "record": "PORTIONS_V_RCT: Comprehensive Intervention for Changing Eating Habits Through Portion Control", "subtitle": "NCT07932977", "detail": "Conditions: Lifestyle Intervention; Weight Management; Behaviour Change; Portion Size. Interventions: Portion control; Healthy lifestyle", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "Clinica Universidad de Navarra, Universidad de Navarra", "enrollment": "181", "nctId": "NCT07932977" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07932977", "url": "https://clinicaltrials.gov/study/NCT07932977", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:04.991Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07931235", "record": "RESIST-EXHALE: Breath Acetone During Tirzepatide Treatment and Resistance Training in Adults With Obesity", "subtitle": "NCT07931235", "detail": "Conditions: Obesity (Disorder). Interventions: Structured resistance training; Tirzepatide", "status": "Not yet recruiting", "fields": { "phase": "Phase not stated", "sponsor": "Technical University of Munich", "enrollment": "150", "nctId": "NCT07931235" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07931235", "url": "https://clinicaltrials.gov/study/NCT07931235", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:04.782Z", "change": null, "origin": "automated" }, { "key": "trial:NCT05433584", "record": "SURPASS-EARLY: A Study of Tirzepatide Compared With Intensified Conventional Care in Adult Participants With Type 2 Diabetes", "subtitle": "NCT05433584", "detail": "Conditions: Type 2 Diabetes. Interventions: Tirzepatide; Antihyperglycemic medication", "status": "Active, not recruiting", "fields": { "phase": "Phase 4", "sponsor": "Eli Lilly and Company", "enrollment": "794", "nctId": "NCT05433584" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT05433584", "url": "https://clinicaltrials.gov/study/NCT05433584", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:04.377Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07931196", "record": "RESIST-EXPLORE: Molecular and Microbiome Changes During Tirzepatide Treatment and Resistance Training in Obesity", "subtitle": "NCT07931196", "detail": "Conditions: Obesity (BMI Equal to or >30). Interventions: Structured resistance training; Tirzepatide", "status": "Not yet recruiting", "fields": { "phase": "Phase not stated", "sponsor": "Technical University of Munich", "enrollment": "150", "nctId": "NCT07931196" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07931196", "url": "https://clinicaltrials.gov/study/NCT07931196", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:05.279Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07475455", "record": "FIPS: Filler Post Market Survey (FIPS)", "subtitle": "NCT07475455", "detail": "Conditions: Wrinkle Reduction. Interventions: Hyaluronic acid dermal filler (routine clinical use)", "status": "Active, not recruiting", "fields": { "phase": "Phase not stated", "sponsor": "Croma-Pharma GmbH", "enrollment": "33", "nctId": "NCT07475455" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07475455", "url": "https://clinicaltrials.gov/study/NCT07475455", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:01.444Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:01.462Z", "change": null, "origin": "automated" }, { "key": "trial:NCT05798494", "record": "PREPARE CHILD: PRE-Pregnancy Weight Loss And the Reducing Effect on CHILDhood Overweight - Aarhus", "subtitle": "NCT05798494", "detail": "Conditions: Overweight and Obesity; Weight Loss; Pregnancy Related; Child Nutrition Sciences; Body Composition. Interventions: Weight loss intervention", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "Ulla Kampmann Opstrup", "enrollment": "66", "nctId": "NCT05798494" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT05798494", "url": "https://clinicaltrials.gov/study/NCT05798494", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:05.226Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07919782", "record": "Study to Evaluate Xtressé Gummy Supplement in Women With Thinning Hair", "subtitle": "NCT07919782", "detail": "Conditions: Androgenetic Alopecia. Interventions: Xtressé Hair Growth Gummies; Placebo Comparator", "status": "Not yet recruiting", "fields": { "phase": "Not applicable", "sponsor": "Restore Biologics Holdings, Inc. dba Xtressé", "enrollment": "30", "nctId": "NCT07919782" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07919782", "url": "https://clinicaltrials.gov/study/NCT07919782", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:02.230Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:02.250Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07517042", "record": "ASCEND-1: Lifestyle Intervention Plus Mazdutide for Weight Management", "subtitle": "NCT07517042", "detail": "Conditions: Obesity; Weight Control. Interventions: Mazdutide; Intensive Lifestyle Intervention; Mazdutide Placebo; Usual Lifestyle Counseling", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "Shanghai Zhongshan Hospital", "enrollment": "420", "nctId": "NCT07517042" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07517042", "url": "https://clinicaltrials.gov/study/NCT07517042", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:04.553Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07880106", "record": "Multimodal Liquid-Biopsy Omics Biomarkers of Treatment Response in Breast Cancer", "subtitle": "NCT07880106", "detail": "Conditions: Lung Cancer Non-small Cell; Colorectal Cancer; Stomach Cancer; Hepatocellular Carcinoma; Breast Cancer", "status": "Recruiting", "fields": { "phase": "Phase not stated", "sponsor": "Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University", "enrollment": "2000", "nctId": "NCT07880106" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07880106", "url": "https://clinicaltrials.gov/study/NCT07880106", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:01.444Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:01.580Z", "change": { "note": "Status changed from “Not yet recruiting” to “Recruiting”", "at": "2026-11-12T18:05:04.767Z", "withinLast7Days": true }, "origin": "automated" }, { "key": "trial:NCT07463846", "record": "A Study to Evaluate ALN-2232 in Participants With Obesity", "subtitle": "NCT07463846", "detail": "Conditions: Obesity. Interventions: ALN-2232; Placebo; Tirzepatide", "status": "Recruiting", "fields": { "phase": "Phase 1 / Phase 2", "sponsor": "Alnylam Pharmaceuticals", "enrollment": "156", "nctId": "NCT07463846" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07463846", "url": "https://clinicaltrials.gov/study/NCT07463846", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:04.493Z", "change": null, "origin": "automated" }, { "key": "trial:NCT00739362", "record": "Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment", "subtitle": "NCT00739362", "detail": "Conditions: Electric Stimulation Therapy; Obesity; Weight Loss; Eating. Interventions: Transcranial Direct Current Stimulation (TDCS); Sham/no-stimulation", "status": "Active, not recruiting", "fields": { "phase": "Phase 2", "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)", "enrollment": "126", "nctId": "NCT00739362" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT00739362", "url": "https://clinicaltrials.gov/study/NCT00739362", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:04.840Z", "change": null, "origin": "automated" }, { "key": "trial:NCT05556512", "record": "SURMOUNT-MMO: A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity", "subtitle": "NCT05556512", "detail": "Conditions: Obesity; Overweight. Interventions: Tirzepatide; Placebo", "status": "Active, not recruiting", "fields": { "phase": "Phase 3", "sponsor": "Eli Lilly and Company", "enrollment": "15374", "nctId": "NCT05556512" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT05556512", "url": "https://clinicaltrials.gov/study/NCT05556512", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:05.100Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07734792", "record": "TOPAZ: Tirzepatide in Thrombectomy-Treated Acute Ischemic Stroke: A Randomized Trial", "subtitle": "NCT07734792", "detail": "Conditions: Acute Ischemic Stroke (AIS). Interventions: Tirzepatide; Standard Medical Care (SMC)", "status": "Recruiting", "fields": { "phase": "Phase 2 / Phase 3", "sponsor": "yifang zhu", "enrollment": "726", "nctId": "NCT07734792" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07734792", "url": "https://clinicaltrials.gov/study/NCT07734792", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:05.336Z", "change": { "note": "Status changed from “Not yet recruiting” to “Recruiting”", "at": "2026-11-12T18:05:05.426Z", "withinLast7Days": true }, "origin": "automated" }, { "key": "trial:NCT07112872", "record": "A Study to Compare Different Doses of Tifeglipron (RO7795081) With Placebo or Semaglutide in People With Type 2 Diabetes", "subtitle": "NCT07112872", "detail": "Conditions: Type 2 Diabetes Mellitus. Interventions: Tifeglipron; Semaglutide; Placebo", "status": "Recruiting", "fields": { "phase": "Phase 2", "sponsor": "Hoffmann-La Roche", "enrollment": "330", "nctId": "NCT07112872" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07112872", "url": "https://clinicaltrials.gov/study/NCT07112872", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:05.158Z", "change": { "note": "Status changed from “Active, not recruiting” to “Recruiting”", "at": "2026-11-12T18:05:05.426Z", "withinLast7Days": true }, "origin": "automated" }, { "key": "trial:NCT07467447", "record": "GZBF: Effect of Retatrutide Versus Placebo in Participants Who Have Obesity or Are Overweight", "subtitle": "NCT07467447", "detail": "Conditions: Obesity. Interventions: Retatrutide (LY3437943); Placebo; Standardized diet and physical activity counseling throughout the study.", "status": "Recruiting", "fields": { "phase": "Phase 2", "sponsor": "Hudson Biotech", "enrollment": "300", "nctId": "NCT07467447" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07467447", "url": "https://clinicaltrials.gov/study/NCT07467447", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:07.948Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:08.021Z", "change": null, "origin": "automated" }, { "key": "trial:NCT03407079", "record": "Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)", "subtitle": "NCT03407079", "detail": "Conditions: Healthy Volunteers; Overweight. Interventions: Sucralose; Placebo", "status": "Recruiting", "fields": { "phase": "Phase 2", "sponsor": "National Institute on Alcohol Abuse and Alcoholism (NIAAA)", "enrollment": "150", "nctId": "NCT03407079" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT03407079", "url": "https://clinicaltrials.gov/study/NCT03407079", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:05.047Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07850063", "record": "ELEVATE-LIVER: A Study to Test Whether Survodutide Helps Improve Heart Structure and Function in People With Overweight or Obesity and Fatty Liver Disease", "subtitle": "NCT07850063", "detail": "Conditions: Obesity; Metabolic Dysfunction-associated Steatotic Liver Disease. Interventions: Survodutide; Placebo matching survodutide", "status": "Not yet recruiting", "fields": { "phase": "Phase 3", "sponsor": "Boehringer Ingelheim", "enrollment": "600", "nctId": "NCT07850063" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07850063", "url": "https://clinicaltrials.gov/study/NCT07850063", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:04.336Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06077864", "record": "A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT)", "subtitle": "NCT06077864", "detail": "Conditions: Obesity. Interventions: survodutide; Placebo", "status": "Completed", "fields": { "phase": "Phase 3", "sponsor": "Boehringer Ingelheim", "enrollment": "5530", "nctId": "NCT06077864" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06077864", "url": "https://clinicaltrials.gov/study/NCT06077864", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T17:35:04.137Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T17:35:04.893Z", "change": null, "origin": "automated" }, { "key": "trial:NCT02911103", "record": "Deep Brain Stimulation Surgery for Focal Hand Dystonia", "subtitle": "NCT02911103", "detail": "Conditions: Dystonia; Focal Dystonia; Musician's Dystonia. Interventions: DBS surgery; Medtronic Activa Rechargeable System", "status": "Active, not recruiting", "fields": { "phase": "Phase 1 / Phase 2", "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)", "enrollment": "5", "nctId": "NCT02911103" }, "jurisdiction": null, "date": "2026-11-12T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT02911103", "url": "https://clinicaltrials.gov/study/NCT02911103", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:01.444Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:01.550Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06318442", "record": "The GAPSID Study - How GLP-1 Analogues Prevent Steroid-Induced Diabetes", "subtitle": "NCT06318442", "detail": "Conditions: Steroid-Induced Diabetes; Steroid Induced Hyperglycemia. Interventions: Semaglutide Oral Product; Metformin Oral Tablet; Placebo", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "Imperial College London", "enrollment": "60", "nctId": "NCT06318442" }, "jurisdiction": null, "date": "2026-11-10T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06318442", "url": "https://clinicaltrials.gov/study/NCT06318442", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:09.947Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:10.384Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06778967", "record": "Optimum 2: A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Adult Type 2 Diabetes Mellitus", "subtitle": "NCT06778967", "detail": "Conditions: Type 2 Diabetes Mellitus (T2DM). Interventions: GZR18; semaglutide", "status": "Completed", "fields": { "phase": "Phase 3", "sponsor": "Gan & Lee Pharmaceuticals.", "enrollment": "1133", "nctId": "NCT06778967" }, "jurisdiction": null, "date": "2026-11-10T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06778967", "url": "https://clinicaltrials.gov/study/NCT06778967", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:09.947Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:10.612Z", "change": null, "origin": "automated" }, { "key": "trial:NCT05773053", "record": "PAOLA: A Study of NT 201 Doses in the Treatment of Platysma Prominence", "subtitle": "NCT05773053", "detail": "Conditions: Platysma Prominence. Interventions: NT 201; NT 201 Placebo", "status": "Completed", "fields": { "phase": "Phase 2", "sponsor": "Merz Aesthetics GmbH", "enrollment": "73", "nctId": "NCT05773053" }, "jurisdiction": null, "date": "2026-11-10T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT05773053", "url": "https://clinicaltrials.gov/study/NCT05773053", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:03.213Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:03.225Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07292441", "record": "GZR18-BWM-303: Extension Study of the Phase 3 Clinical Study of GZR18 Injection for Weight Loss", "subtitle": "NCT07292441", "detail": "Conditions: Overweight or Obesity. Interventions: GZR18 injection; Placebo", "status": "Completed", "fields": { "phase": "Phase 3", "sponsor": "Gan & Lee Pharmaceuticals.", "enrollment": "224", "nctId": "NCT07292441" }, "jurisdiction": null, "date": "2026-11-10T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07292441", "url": "https://clinicaltrials.gov/study/NCT07292441", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-12T11:35:12.390Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-12T11:35:12.841Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07929298", "record": "A Study to Evaluate the Safety and Efficacy of Ecnoglutide Tablets in Chinese Participants With Overweight or Obesity", "subtitle": "NCT07929298", "detail": "Conditions: Overweight , Obesity; Weight Management. Interventions: ecnoglutide tablet; placebo with matching dosage", "status": "Not yet recruiting", "fields": { "phase": "Phase 2", "sponsor": "Hangzhou Sciwind Biosciences Co., Ltd.", "enrollment": "180", "nctId": "NCT07929298" }, "jurisdiction": null, "date": "2026-11-10T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07929298", "url": "https://clinicaltrials.gov/study/NCT07929298", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-12T11:35:12.390Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-12T11:35:12.751Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07929233", "record": "CLEAR-GLP1: 24-hour Clear Liquid Diet vs. Standard Fasting for Upper Gastrointestinal Endoscopy in Patients Taking Agonists of the GLP-1 Receptor", "subtitle": "NCT07929233", "detail": "Conditions: Retained Gastric Content; Delayed Gastric Emptying; Obesity; Type 2 Diabetes Mellitus (DM). Interventions: 24-Hour Clear Liquid Diet; Standard Fasting", "status": "Not yet recruiting", "fields": { "phase": "Not applicable", "sponsor": "Portuguese Oncology Institute, Coimbra", "enrollment": "250", "nctId": "NCT07929233" }, "jurisdiction": null, "date": "2026-11-10T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07929233", "url": "https://clinicaltrials.gov/study/NCT07929233", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:09.947Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:10.570Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07830329", "record": "Efficacy and Safety of Olatorepatide Versus Placebo in Adults With Moderate to Severe Hidradenitis Suppurativa Living With Overweight or Obesity", "subtitle": "NCT07830329", "detail": "Conditions: Hidradenitis Suppurativa. Interventions: Olatorepatide; Placebo", "status": "Recruiting", "fields": { "phase": "Phase 2", "sponsor": "Regeneron Pharmaceuticals", "enrollment": "300", "nctId": "NCT07830329" }, "jurisdiction": null, "date": "2026-11-10T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07830329", "url": "https://clinicaltrials.gov/study/NCT07830329", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-12T11:35:12.390Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-12T11:35:12.659Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07929831", "record": "IMPACT: The Impact of Incretins on Fat-free Mass, Muscle Strength and Functional Capacity", "subtitle": "NCT07929831", "detail": "Conditions: Obesity & Overweight", "status": "Recruiting", "fields": { "phase": "Phase not stated", "sponsor": "Radboud University Medical Center", "enrollment": "200", "nctId": "NCT07929831" }, "jurisdiction": null, "date": "2026-11-10T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07929831", "url": "https://clinicaltrials.gov/study/NCT07929831", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:09.947Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:10.489Z", "change": null, "origin": "automated" }, { "key": "trial:NCT05925959", "record": "Preoperative Weight Loss for Open Abdominal Wall Reconstruction", "subtitle": "NCT05925959", "detail": "Conditions: Abdominal Wall Hernia. Interventions: Preoperative Weight Management Program", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "Benjamin T. Miller", "enrollment": "258", "nctId": "NCT05925959" }, "jurisdiction": null, "date": "2026-11-10T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT05925959", "url": "https://clinicaltrials.gov/study/NCT05925959", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:09.947Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:10.442Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06162715", "record": "GRABS-0: GLP-1 Receptor Agonists Post-Bariatric Surgery (GRABS) Pilot Trial", "subtitle": "NCT06162715", "detail": "Conditions: Severe Obesity; Obesity; BMI Greater Than 30. Interventions: Tirzepatide; Standard of Care post-gastric bypass", "status": "Active, not recruiting", "fields": { "phase": "Phase 2 / Phase 3", "sponsor": "Vanderbilt University Medical Center", "enrollment": "30", "nctId": "NCT06162715" }, "jurisdiction": null, "date": "2026-11-10T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06162715", "url": "https://clinicaltrials.gov/study/NCT06162715", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:08.933Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:09.277Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07929571", "record": "RESIST-MIND: Functional, Cognitive, and Behavioral Correlates of Resistance Training During Tirzepatide-Induced Weight Loss", "subtitle": "NCT07929571", "detail": "Conditions: Obesity (Disorder). Interventions: Structured resistance training; Tirzepatide", "status": "Not yet recruiting", "fields": { "phase": "Phase not stated", "sponsor": "Technical University of Munich", "enrollment": "150", "nctId": "NCT07929571" }, "jurisdiction": null, "date": "2026-11-10T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07929571", "url": "https://clinicaltrials.gov/study/NCT07929571", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:08.933Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:09.424Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07400107", "record": "AMAZE 8: AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight", "subtitle": "NCT07400107", "detail": "Conditions: Obesity; Overweight; Diabetes Mellitus, Type 2. Interventions: NNC0487-0111; Semaglutide; Placebo (matched to NNC0487-0111); Placebo (matched to semaglutide)", "status": "Active, not recruiting", "fields": { "phase": "Phase 3", "sponsor": "Novo Nordisk A/S", "enrollment": "985", "nctId": "NCT07400107" }, "jurisdiction": null, "date": "2026-11-10T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07400107", "url": "https://clinicaltrials.gov/study/NCT07400107", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:09.947Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:10.529Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07232719", "record": "TRIUMPH-8: A Study of Retatrutide (LY3437943) in Participants With Obesity or Overweight", "subtitle": "NCT07232719", "detail": "Conditions: Obesity; Overweight. Interventions: Retatrutide; Placebo", "status": "Active, not recruiting", "fields": { "phase": "Phase 3", "sponsor": "Eli Lilly and Company", "enrollment": "250", "nctId": "NCT07232719" }, "jurisdiction": null, "date": "2026-11-10T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07232719", "url": "https://clinicaltrials.gov/study/NCT07232719", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:07.948Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:08.065Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07832032", "record": "BioM: Biological Profiles of Neuropeptides, Neurotrophins and miRNA in Migraine", "subtitle": "NCT07832032", "detail": "Conditions: Migraine. Interventions: Rimegepant 75 MG", "status": "Enrolling by invitation", "fields": { "phase": "Phase not stated", "sponsor": "Nordlandssykehuset HF", "enrollment": "60", "nctId": "NCT07832032" }, "jurisdiction": null, "date": "2026-11-10T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07832032", "url": "https://clinicaltrials.gov/study/NCT07832032", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:05.068Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:05.082Z", "change": { "note": "Status changed from “Not yet recruiting” to “Enrolling by invitation”", "at": "2026-11-10T17:05:06.973Z", "withinLast7Days": true }, "origin": "automated" }, { "key": "trial:NCT03984955", "record": "CITTE: Comparing Injection Treatments for Tennis Elbow", "subtitle": "NCT03984955", "detail": "Conditions: Tennis Elbow; Lateral Epicondylitis; Elbows Tendonitis. Interventions: Sodium hyaluronate with mannitol (Ostenil Tendon); Platelet-Rich Plasma Injection; Subcutaneous sham injection", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "Wrightington, Wigan and Leigh NHS Foundation Trust", "enrollment": "123", "nctId": "NCT03984955" }, "jurisdiction": null, "date": "2026-11-09T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT03984955", "url": "https://clinicaltrials.gov/study/NCT03984955", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:01.444Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:01.665Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06347094", "record": "PRE-CARE-DIET: Precision Nutrition to Improve Cardiometabolic Health With Dietary (Poly)Phenols", "subtitle": "NCT06347094", "detail": "Conditions: Individual Variability in (Poly)Phenol Metabolism; Cardiometabolic Health; Personalized Dietary Intervention; Obesity. Interventions: Personalized Dietary Plan; Oral (Poly)phenol Challenge Test (OPCT); General Dietary Advice", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "University of Parma", "enrollment": "330", "nctId": "NCT06347094" }, "jurisdiction": null, "date": "2026-11-09T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06347094", "url": "https://clinicaltrials.gov/study/NCT06347094", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-12T11:35:12.390Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-12T11:35:13.342Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07391267", "record": "Pathogenesis of Chronic Kidney Disease Associated With Metabolic Dysfunction- Associated Fatty Liver Disease (MAFLD) and Treatment Response of Oral Semaglutide.", "subtitle": "NCT07391267", "detail": "Conditions: Chronic Kidney Diseases; MAFLD. Interventions: Semaglutide Oral Tablet; Placebo; Standard medical treatment", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "Institute of Liver and Biliary Sciences, India", "enrollment": "90", "nctId": "NCT07391267" }, "jurisdiction": null, "date": "2026-11-09T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07391267", "url": "https://clinicaltrials.gov/study/NCT07391267", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:09.947Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:10.791Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07770152", "record": "GLP1: Semaglutide in Youth With Autism Spectrum Disorder", "subtitle": "NCT07770152", "detail": "Conditions: Autism Spectrum Disorder; Obesity. Interventions: Glucagon-like peptide-1 receptor agonist：Semaglutide; Lifestyle Management (LSM) Counseling", "status": "Recruiting", "fields": { "phase": "Phase 4", "sponsor": "Children's Hospital Medical Center, Cincinnati", "enrollment": "42", "nctId": "NCT07770152" }, "jurisdiction": null, "date": "2026-11-09T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07770152", "url": "https://clinicaltrials.gov/study/NCT07770152", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:09.947Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:10.736Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07926152", "record": "COMPACT: Exercise and Protein to Reduce Muscle Loss During GLP-1-Based Treatment in Type 2 Diabetes", "subtitle": "NCT07926152", "detail": "Conditions: Type 2 Diabetes (T2DM); Obesity & Overweight; Sarcopenia. Interventions: Supervised exercise training; protein supplement; Standardized lifestyle counseling", "status": "Not yet recruiting", "fields": { "phase": "Not applicable", "sponsor": "German Diabetes Center", "enrollment": "94", "nctId": "NCT07926152" }, "jurisdiction": null, "date": "2026-11-09T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07926152", "url": "https://clinicaltrials.gov/study/NCT07926152", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:09.947Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:10.694Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07924267", "record": "SERINITY: A Single Ascending Dose and Multiple Ascending Dose Trial to Assess the Dose, the Efficacy and Oro-sensitivity of Two Modified Linoleic Acids NKS-3 and NKS-5", "subtitle": "NCT07924267", "detail": "Conditions: Obesity & Overweight; Overweight (BMI > 30). Interventions: NKS-3; NKS-5", "status": "Completed", "fields": { "phase": "Phase 1", "sponsor": "EktaH", "enrollment": "120", "nctId": "NCT07924267" }, "jurisdiction": null, "date": "2026-11-09T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07924267", "url": "https://clinicaltrials.gov/study/NCT07924267", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-12T11:35:12.390Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-12T11:35:13.069Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07924553", "record": "Efficacy, Safety and Cardiovascular Protection of Mazdutide in Type 1 Diabetes", "subtitle": "NCT07924553", "detail": "Conditions: Type 1 Diabetes. Interventions: Mazdutide; Placbo", "status": "Not yet recruiting", "fields": { "phase": "Not applicable", "sponsor": "Peking University People's Hospital", "enrollment": "182", "nctId": "NCT07924553" }, "jurisdiction": null, "date": "2026-11-09T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07924553", "url": "https://clinicaltrials.gov/study/NCT07924553", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-12T11:35:12.390Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-12T11:35:13.251Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07924618", "record": "Ocular Changes in Patients Using Tirzepatide or Semaglutide", "subtitle": "NCT07924618", "detail": "Conditions: Type 2 Diabetes Mellitus; Obesity. Interventions: Semaglutide; Tirzepatide", "status": "Recruiting", "fields": { "phase": "Phase not stated", "sponsor": "Istanbul University", "enrollment": "40", "nctId": "NCT07924618" }, "jurisdiction": null, "date": "2026-11-09T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07924618", "url": "https://clinicaltrials.gov/study/NCT07924618", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:09.947Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:10.653Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07351045", "record": "Enith1: A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes", "subtitle": "NCT07351045", "detail": "Conditions: Obesity or Overweight. Interventions: Placebo; Enicepatide", "status": "Recruiting", "fields": { "phase": "Phase 3", "sponsor": "Hoffmann-La Roche", "enrollment": "2000", "nctId": "NCT07351045" }, "jurisdiction": null, "date": "2026-11-09T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07351045", "url": "https://clinicaltrials.gov/study/NCT07351045", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-12T11:35:12.390Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-12T11:35:12.984Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07351058", "record": "Enith2: A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes", "subtitle": "NCT07351058", "detail": "Conditions: Obesity or Overweight; Type 2 Diabetes Mellitus. Interventions: Placebo; Enicepatide", "status": "Recruiting", "fields": { "phase": "Phase 3", "sponsor": "Hoffmann-La Roche", "enrollment": "1600", "nctId": "NCT07351058" }, "jurisdiction": null, "date": "2026-11-09T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07351058", "url": "https://clinicaltrials.gov/study/NCT07351058", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-12T11:35:12.390Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-12T11:35:13.206Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07775404", "record": "Elecoglipron: A Study to Investigate the Efficacy and Safety of Elecoglipron in Asian Participants With Obesity or Overweight With or Without Type 2 Diabetes Mellitus", "subtitle": "NCT07775404", "detail": "Conditions: Obesity; Overweight. Interventions: Elecoglipron; Placebo", "status": "Recruiting", "fields": { "phase": "Phase 3", "sponsor": "AstraZeneca", "enrollment": "351", "nctId": "NCT07775404" }, "jurisdiction": null, "date": "2026-11-09T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07775404", "url": "https://clinicaltrials.gov/study/NCT07775404", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-12T11:35:12.390Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-12T11:35:12.885Z", "change": null, "origin": "automated" }, { "key": "trial:NCT05936151", "record": "A Study of Retatrutide (LY3437943) on Renal Function in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes", "subtitle": "NCT05936151", "detail": "Conditions: Overweight or Obesity; CKD; Type 2 Diabetes. Interventions: Retatrutide; Placebo", "status": "Completed", "fields": { "phase": "Phase 2", "sponsor": "Eli Lilly and Company", "enrollment": "146", "nctId": "NCT05936151" }, "jurisdiction": null, "date": "2026-11-09T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT05936151", "url": "https://clinicaltrials.gov/study/NCT05936151", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:07.948Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:08.105Z", "change": { "note": "Results first posted on ClinicalTrials.gov (2026-11-09)", "at": "2026-11-09T14:35:06.951Z", "withinLast7Days": true }, "origin": "automated" }, { "key": "trial:NCT07806474", "record": "Efficacy and Safety of Two Hair Supplements in Men With Androgenic Alopecia", "subtitle": "NCT07806474", "detail": "Conditions: Androgenic Alopecia; Healthy Adult Male. Interventions: formulation of green tea leaf extract, bamboo shoot extract and selenium-enriched yeast; formulation of grape seed extr…", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "Activ'inside", "enrollment": "99", "nctId": "NCT07806474" }, "jurisdiction": null, "date": "2026-11-09T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07806474", "url": "https://clinicaltrials.gov/study/NCT07806474", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:02.230Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:02.372Z", "change": { "note": "Status changed from “Not yet recruiting” to “Recruiting”", "at": "2026-11-09T16:05:03.759Z", "withinLast7Days": true }, "origin": "automated" }, { "key": "trial:NCT07923357", "record": "A Phase 2 Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of SAL0150 Tablets in Subjects With Type 2 Diabetes Mellitus", "subtitle": "NCT07923357", "detail": "Conditions: Type 2 Diabetes Mellitus (T2DM); Type 2 Diabetes; T2DM. Interventions: SAL0150 dose 1; SAL0150 dose 2; SAL0150 dose 2; SAL0150 dose 3; SAL0150 dose 3; Placebo; Semaglutide inject 1.0 mg", "status": "Not yet recruiting", "fields": { "phase": "Phase 2", "sponsor": "Shenzhen Salubris Pharmaceuticals Co., Ltd.", "enrollment": "364", "nctId": "NCT07923357" }, "jurisdiction": null, "date": "2026-11-06T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07923357", "url": "https://clinicaltrials.gov/study/NCT07923357", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:09.947Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:10.874Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07923630", "record": "VITAL-H: Validation & Intervention Testing for Aging, Longevity and Healthspan", "subtitle": "NCT07923630", "detail": "Conditions: Aging; Functional Decline. Interventions: Dapagliflozin 10Mg Oral Tablet; Semaglutide oral; Placebo", "status": "Not yet recruiting", "fields": { "phase": "Phase 2", "sponsor": "The University of Texas Health Science Center at San Antonio", "enrollment": "1200", "nctId": "NCT07923630" }, "jurisdiction": null, "date": "2026-11-06T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07923630", "url": "https://clinicaltrials.gov/study/NCT07923630", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-12T06:05:03.507Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-12T06:05:04.046Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07529977", "record": "MINORA-MEN: Phase 3 Study to Evaluate the Efficacy and Safety of Oral Minoxidil (N1087) in Men With Androgenetic Alopecia.", "subtitle": "NCT07529977", "detail": "Conditions: Androgenetic Alopecia; Androgenetic Alopecia (AGA). Interventions: Minoxidil oral solution; Placebo oral solution", "status": "Not yet recruiting", "fields": { "phase": "Phase 3", "sponsor": "Eurofarma Laboratorios S.A.", "enrollment": "372", "nctId": "NCT07529977" }, "jurisdiction": null, "date": "2026-11-06T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07529977", "url": "https://clinicaltrials.gov/study/NCT07529977", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:02.230Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:02.451Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07923448", "record": "toxin: Can TrenibotulinumtoxinE Reverse OnabotulinumtoxinA Effect in Treating Lateral Canthal Lines?", "subtitle": "NCT07923448", "detail": "Conditions: Wrinkles and Rhytides. Interventions: TrenibotulinumtoxinE and OnabotulinumtoxinA; Onabotulinumtoxin A followed by placebo", "status": "Not yet recruiting", "fields": { "phase": "Phase 2", "sponsor": "Project Skin MD", "enrollment": "4", "nctId": "NCT07923448" }, "jurisdiction": null, "date": "2026-11-06T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07923448", "url": "https://clinicaltrials.gov/study/NCT07923448", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:01.444Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:01.693Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07651319", "record": "Interleukine-2 (IL-2) Plus Semaglutide in Alzheimer's Disease", "subtitle": "NCT07651319", "detail": "Conditions: Alzheimer Dementia (AD). Interventions: IL-2 (Aldesleukin); Semaglutide Plus IL-2; Placebo", "status": "Recruiting", "fields": { "phase": "Phase 1 / Phase 2", "sponsor": "The Methodist Hospital Research Institute", "enrollment": "30", "nctId": "NCT07651319" }, "jurisdiction": null, "date": "2026-11-06T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07651319", "url": "https://clinicaltrials.gov/study/NCT07651319", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-13T06:35:13.538Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-13T06:35:14.557Z", "change": null, "origin": "automated" }, { "key": "trial:NCT04873245", "record": "QUEST: Lifestyle Counseling and Medication for Adolescent Weight Management", "subtitle": "NCT04873245", "detail": "Conditions: Obesity, Childhood. Interventions: Intensive Behavioral Program; Semaglutide and Behavioral Program", "status": "Completed", "fields": { "phase": "Phase 2", "sponsor": "University of Minnesota", "enrollment": "121", "nctId": "NCT04873245" }, "jurisdiction": null, "date": "2026-11-06T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT04873245", "url": "https://clinicaltrials.gov/study/NCT04873245", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-12T06:05:03.507Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-12T06:05:03.939Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07907783", "record": "AWAKENING: Phase 2 Efficacy and Safety of PP405 in Adult Females With Androgenetic Alopecia", "subtitle": "NCT07907783", "detail": "Conditions: Androgenetic Alopecia. Interventions: PP405 0.05% Topical Gel; Vehicle Topical Gel", "status": "Not yet recruiting", "fields": { "phase": "Phase 2", "sponsor": "Pelage Pharmaceuticals, Inc.", "enrollment": "200", "nctId": "NCT07907783" }, "jurisdiction": null, "date": "2026-11-06T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07907783", "url": "https://clinicaltrials.gov/study/NCT07907783", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:02.230Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:02.412Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07901777", "record": "GLP-BARI-VAN: Two-Year Weight Loss With GLP-1 Medications Compared With Sleeve Gastrectomy in Adults With Obesity", "subtitle": "NCT07901777", "detail": "Conditions: Obesity & Overweight. Interventions: GLP-1 Receptor Agonist Therapy; Laparoscopic Sleeve Gastrectomy", "status": "Recruiting", "fields": { "phase": "Phase not stated", "sponsor": "Yuzuncu Yil University", "enrollment": "200", "nctId": "NCT07901777" }, "jurisdiction": null, "date": "2026-11-06T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07901777", "url": "https://clinicaltrials.gov/study/NCT07901777", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:06.920Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:07.058Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07639684", "record": "MEASURE: Impact of Endoscopic Sleeve Gastroplasty (ESG) in Obese Adults With Type 2 Diabetes (T2D)", "subtitle": "NCT07639684", "detail": "Conditions: Type 2 Diabetes Mellitus (T2D); Obesity (BMI>30). Interventions: ESG with OverStitch", "status": "Not yet recruiting", "fields": { "phase": "Not applicable", "sponsor": "Boston Scientific Corporation", "enrollment": "50", "nctId": "NCT07639684" }, "jurisdiction": null, "date": "2026-11-06T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07639684", "url": "https://clinicaltrials.gov/study/NCT07639684", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-10T09:35:10.280Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-10T09:35:11.014Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07575399", "record": "Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)", "subtitle": "NCT07575399", "detail": "Conditions: Obesity or Overweight. Interventions: Maridebart Cafraglutide", "status": "Recruiting", "fields": { "phase": "Phase 3", "sponsor": "Amgen", "enrollment": "300", "nctId": "NCT07575399" }, "jurisdiction": null, "date": "2026-11-06T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07575399", "url": "https://clinicaltrials.gov/study/NCT07575399", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-10T09:35:10.280Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-10T09:35:10.831Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07210463", "record": "PLATINUM EU: A Study of NT 201 in Adults With Moderate to Severe Platysma Prominence in Europe (PLATINUM EU)", "subtitle": "NCT07210463", "detail": "Conditions: Neuromuscular Agents; Peripheral Nervous System Agents; Physiological Effects of Drugs; Acetylcholine Release Inhibitors; Membrane Transpor…. Interventions: NT 201; NT 201 Placebo", "status": "Active, not recruiting", "fields": { "phase": "Phase 3", "sponsor": "Merz Aesthetics GmbH", "enrollment": "300", "nctId": "NCT07210463" }, "jurisdiction": null, "date": "2026-11-06T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07210463", "url": "https://clinicaltrials.gov/study/NCT07210463", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:03.213Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:03.261Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07685808", "record": "Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes", "subtitle": "NCT07685808", "detail": "Conditions: Overweight or Obesity. Interventions: Olatorepatide; Placebo", "status": "Recruiting", "fields": { "phase": "Phase 2", "sponsor": "Regeneron Pharmaceuticals", "enrollment": "360", "nctId": "NCT07685808" }, "jurisdiction": null, "date": "2026-11-06T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07685808", "url": "https://clinicaltrials.gov/study/NCT07685808", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-12T11:35:12.390Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-12T11:35:13.493Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07163624", "record": "T2DM: UBT251 Injection Phase II (Type 2 Diabetes Mellitus) Study", "subtitle": "NCT07163624", "detail": "Conditions: Type 2 Diabetes Mellitus (T2DM). Interventions: UBT251 Injection 2.0 mg and UBT251 Injection Placebo; UBT251 Injection 4.0 mg (ID 0.5 mg) and UBT251 Injection Placebo;…", "status": "Completed", "fields": { "phase": "Phase 2", "sponsor": "The United Bio-Technology (Hengqin) Co., Ltd.", "enrollment": "211", "nctId": "NCT07163624" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07163624", "url": "https://clinicaltrials.gov/study/NCT07163624", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-12T06:05:03.507Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-12T06:05:04.147Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06913023", "record": "SPOT-DM: Semaglutide for the Prevention Of Post-Transplant Diabetes Mellitus", "subtitle": "NCT06913023", "detail": "Conditions: Kidney Transplant Recipient. Interventions: Semaglutide 0.25 mg; Semaglutide 0.5 mg; Semaglutide 1.0 mg; Semaglutide 1.7mg subcutaneous; Semaglutide 2.4 MG/0.75 ML…", "status": "Not yet recruiting", "fields": { "phase": "Phase 2 / Phase 3", "sponsor": "University Health Network, Toronto", "enrollment": "37", "nctId": "NCT06913023" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06913023", "url": "https://clinicaltrials.gov/study/NCT06913023", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-12T06:05:03.507Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-12T06:05:04.114Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07919886", "record": "Evaluation of the Efficacy and Safety of Fractional CO₂ Laser With and Without Intradermal Botulinum Toxin A in the Treatment of Inflammatory Facial Acne Vulgaris.", "subtitle": "NCT07919886", "detail": "Conditions: Acne; Acne Papulopustulosa. Interventions: Fractional co2 laser; Botulinium Toxin-A", "status": "Not yet recruiting", "fields": { "phase": "Phase 3", "sponsor": "Cairo University", "enrollment": "24", "nctId": "NCT07919886" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07919886", "url": "https://clinicaltrials.gov/study/NCT07919886", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:01.444Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:01.930Z", "change": null, "origin": "automated" }, { "key": "trial:NCT03474718", "record": "Evaluating the Efficacy of Platelet-rich Plasma Therapy in the Treatment of Androgenic Alopecia", "subtitle": "NCT03474718", "detail": "Conditions: Androgenic Alopecia. Interventions: Platelet-rich Plasma Left Side; Platelet-rich Plasma Right Side", "status": "Not yet recruiting", "fields": { "phase": "Early phase 1", "sponsor": "Wake Forest University Health Sciences", "enrollment": "16", "nctId": "NCT03474718" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT03474718", "url": "https://clinicaltrials.gov/study/NCT03474718", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:02.230Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:02.489Z", "change": null, "origin": "automated" }, { "key": "trial:NCT05243368", "record": "Evaluation of Personalized Nutritional Intervention on Wound Healing of Cutaneous Ulcers in Diabetics", "subtitle": "NCT05243368", "detail": "Conditions: Foot, Diabetic. Interventions: Personalized Nutritional Intervention", "status": "Active, not recruiting", "fields": { "phase": "Not applicable", "sponsor": "Maimónides Biomedical Research Institute of Córdoba", "enrollment": "30", "nctId": "NCT05243368" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT05243368", "url": "https://clinicaltrials.gov/study/NCT05243368", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:01.444Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:01.797Z", "change": null, "origin": "automated" }, { "key": "trial:NCT05133739", "record": "RHA®4 for Midface Volume Deficiency", "subtitle": "NCT05133739", "detail": "Conditions: Cheek Augmentation; Correction of Age-related Midface Contour Deficiencies. Interventions: injection of RHA®4 in Midface; injection of Comparator Product in Midface", "status": "Completed", "fields": { "phase": "Phase not stated", "sponsor": "Teoxane SA", "enrollment": "201", "nctId": "NCT05133739" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT05133739", "url": "https://clinicaltrials.gov/study/NCT05133739", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:01.444Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:01.769Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07918443", "record": "Volido PAS: Post-Approval Study of Saypha® ChIQ™ for Midface Augmentation in Subjects With Fitzpatrick Skin Types V and VI", "subtitle": "NCT07918443", "detail": "Conditions: Moderate to Severe Midface Volume Deficit. Interventions: Crosslinked hyaluronic acid dermal filler with lidocaine", "status": "Not yet recruiting", "fields": { "phase": "Not applicable", "sponsor": "Croma-Pharma GmbH", "enrollment": "45", "nctId": "NCT07918443" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07918443", "url": "https://clinicaltrials.gov/study/NCT07918443", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:01.444Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:01.897Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07919964", "record": "Exosomes for Striae Distensae", "subtitle": "NCT07919964", "detail": "Conditions: Striae Distensae. Interventions: Micro needling then exosome application topically; Micro needling", "status": "Completed", "fields": { "phase": "Not applicable", "sponsor": "Tanta University", "enrollment": "20", "nctId": "NCT07919964" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07919964", "url": "https://clinicaltrials.gov/study/NCT07919964", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:01.444Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:01.958Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07919405", "record": "REDEFINE: A Research Study to Investigate How Well the Medicine CagriSema Lowers High Blood Pressure in People Living With High Blood Pressure and Obesity", "subtitle": "NCT07919405", "detail": "Conditions: Hypertension; Obesity. Interventions: CagriSema; Semaglutide; Cagrilintide; Placebo", "status": "Not yet recruiting", "fields": { "phase": "Phase 3", "sponsor": "Novo Nordisk A/S", "enrollment": "1408", "nctId": "NCT07919405" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07919405", "url": "https://clinicaltrials.gov/study/NCT07919405", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:05.068Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:05.158Z", "change": null, "origin": "automated" }, { "key": "trial:NCT04990024", "record": "The Effect of Different Diets on Arterial Stiffness in Obese Patients on Semaglutide", "subtitle": "NCT04990024", "detail": "Conditions: Obesity; Weight Loss. Interventions: Dietary Intervention Med Diet; Dietary Intervention HP/LC Diet", "status": "Completed", "fields": { "phase": "Not applicable", "sponsor": "American University of Beirut Medical Center", "enrollment": "31", "nctId": "NCT04990024" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT04990024", "url": "https://clinicaltrials.gov/study/NCT04990024", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-10T09:35:10.280Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-10T09:35:11.080Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07918846", "record": "Enith-MACE: A Clinical Study Testing Enicepatide in Participants Living With Overweight or Obesity and Cardiovascular Disease", "subtitle": "NCT07918846", "detail": "Conditions: Overweight; Obesity; Cardiovascular Disease. Interventions: Enicepatide; Placebo", "status": "Not yet recruiting", "fields": { "phase": "Phase 3", "sponsor": "Hoffmann-La Roche", "enrollment": "8200", "nctId": "NCT07918846" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07918846", "url": "https://clinicaltrials.gov/study/NCT07918846", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-10T09:35:10.280Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-10T09:35:11.048Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06973720", "record": "VESPER-3: A Phase 2b Study to Evaluate the Efficacy and Safety of Once-Monthly MET097 in Adults With Obesity or Overweight", "subtitle": "NCT06973720", "detail": "Conditions: Obesity; Overweight or Obesity. Interventions: MET097; Placebo", "status": "Completed", "fields": { "phase": "Phase 2", "sponsor": "Pfizer", "enrollment": "268", "nctId": "NCT06973720" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06973720", "url": "https://clinicaltrials.gov/study/NCT06973720", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-09T08:05:04.880Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-09T08:05:05.516Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07919678", "record": "A Study to Learn About Study Medicine Called Berobenatide in Adults With Knee Pain and Overweight or Obesity (VESPER-OA 1)", "subtitle": "NCT07919678", "detail": "Conditions: Obesity; Overweight; Osteoarthritis of the Knee. Interventions: Berobenatide; Placebo", "status": "Recruiting", "fields": { "phase": "Phase 3", "sponsor": "Pfizer", "enrollment": "656", "nctId": "NCT07919678" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07919678", "url": "https://clinicaltrials.gov/study/NCT07919678", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-09T08:05:04.880Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-09T08:05:05.250Z", "change": null, "origin": "automated" }, { "key": "trial:NCT04194424", "record": "A Multidisciplinary Weight Loss Program at AUB-MC", "subtitle": "NCT04194424", "detail": "Conditions: Obesity; Weight Loss. Interventions: Multidisciplinary weight loss program; Standard Care; Metformin Hcl 850Mg Tab", "status": "Active, not recruiting", "fields": { "phase": "Not applicable", "sponsor": "American University of Beirut Medical Center", "enrollment": "20", "nctId": "NCT04194424" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT04194424", "url": "https://clinicaltrials.gov/study/NCT04194424", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-10T09:35:10.280Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-10T09:35:11.160Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07111494", "record": "Impact of Glucagon-like Peptide-1 (GLP-1) Analogs on Disease Outcomes in Psoriatic Arthritis: A Pragmatic Randomized Controlled Trial", "subtitle": "NCT07111494", "detail": "Conditions: Psoriatic Arthritis (PsA). Interventions: GLP-1 agonists; Nutrition Counseling", "status": "Recruiting", "fields": { "phase": "Phase 4", "sponsor": "Medical College of Wisconsin", "enrollment": "22", "nctId": "NCT07111494" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07111494", "url": "https://clinicaltrials.gov/study/NCT07111494", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-09T08:05:04.880Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-09T08:05:05.324Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06593314", "record": "Using Ultromics EchoGo HFpEF Algorithm to Identify and Treat High Heart Failure Risk in Patients With Type 2 Diabetes", "subtitle": "NCT06593314", "detail": "Conditions: Heart Failure; Diabetes. Interventions: Message with EchoGo; Standard Message", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "University of Texas Southwestern Medical Center", "enrollment": "800", "nctId": "NCT06593314" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06593314", "url": "https://clinicaltrials.gov/study/NCT06593314", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-09T08:05:04.880Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-09T08:05:05.580Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07871513", "record": "A Study to Assess the Safety and Efficacy of Co-Reconstituted TrenibotulinumtoxinE and OnabotulinumtoxinA in Adult Participants With Moderate to Severe Upper Facial Lines", "subtitle": "NCT07871513", "detail": "Conditions: Upper Facial Lines; Glabellar Lines. Interventions: TrenibotulinumtoxinE and OnabotulinumtoxinA; Placebo; OnabotulinumtoxinA", "status": "Recruiting", "fields": { "phase": "Phase 2", "sponsor": "AbbVie", "enrollment": "300", "nctId": "NCT07871513" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07871513", "url": "https://clinicaltrials.gov/study/NCT07871513", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:03.213Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:03.298Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07866066", "record": "MARITIME-T2D-3: Maridebart Cafraglutide Versus Semaglutide in Participants With Type 2 Diabetes", "subtitle": "NCT07866066", "detail": "Conditions: Diabetes Mellitus, Type 2. Interventions: Maridebart cafraglutide; Semaglutide", "status": "Recruiting", "fields": { "phase": "Phase 3", "sponsor": "Amgen", "enrollment": "1300", "nctId": "NCT07866066" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07866066", "url": "https://clinicaltrials.gov/study/NCT07866066", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-12T06:05:03.507Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-12T06:05:04.224Z", "change": { "note": "Status changed from “Not yet recruiting” to “Recruiting”", "at": "2026-11-05T15:35:04.481Z", "withinLast7Days": false }, "origin": "automated" }, { "key": "trial:NCT07670416", "record": "A Study to Evaluate the Effects of Enicepatide in Participants With Obesity or Overweight, With or Without Type 2 Diabetes", "subtitle": "NCT07670416", "detail": "Conditions: Obesity; Overweight; Type 2 Diabetes Mellitus (T2DM). Interventions: Enicepatide; Placebo", "status": "Recruiting", "fields": { "phase": "Phase 3", "sponsor": "Hoffmann-La Roche", "enrollment": "300", "nctId": "NCT07670416" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07670416", "url": "https://clinicaltrials.gov/study/NCT07670416", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-09T08:05:04.880Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-09T08:05:05.378Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07668336", "record": "ACHIEVE-PEDS: A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes", "subtitle": "NCT07668336", "detail": "Conditions: Diabetes Mellitus, Type 2. Interventions: Orforglipron; Dulaglutide", "status": "Recruiting", "fields": { "phase": "Phase 3", "sponsor": "Eli Lilly and Company", "enrollment": "170", "nctId": "NCT07668336" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07668336", "url": "https://clinicaltrials.gov/study/NCT07668336", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:05.987Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:06.001Z", "change": { "note": "Status changed from “Not yet recruiting” to “Recruiting”", "at": "2026-10-19T23:35:08.309Z", "withinLast7Days": false }, "origin": "automated" }, { "key": "trial:NCT07794579", "record": "ATTAIN-NOW: A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity", "subtitle": "NCT07794579", "detail": "Conditions: Overweight; Prediabetic State; Prehypertension; Obesity, Abdominal. Interventions: Orforglipron; Placebo", "status": "Recruiting", "fields": { "phase": "Phase 3", "sponsor": "Eli Lilly and Company", "enrollment": "2001", "nctId": "NCT07794579" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07794579", "url": "https://clinicaltrials.gov/study/NCT07794579", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:05.987Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:06.040Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07575932", "record": "SOLIS-1: A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity", "subtitle": "NCT07575932", "detail": "Conditions: Overweight; Obesity; Overweight and/or Obesity; Overweight or Obesity; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseas…. Interventions: PF-08653945; PF-08653944; Placebo", "status": "Active, not recruiting", "fields": { "phase": "Phase 2", "sponsor": "Pfizer", "enrollment": "940", "nctId": "NCT07575932" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07575932", "url": "https://clinicaltrials.gov/study/NCT07575932", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:05.068Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:05.121Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07845500", "record": "A Study to Learn About Switching to a Monthly Study Medicine Called Berobenatide (PF-08653944) to Help Keep Weight Off in People With Overweight or Obesity", "subtitle": "NCT07845500", "detail": "Conditions: Obesity; Overweight and/or Obesity; Overweight; Treatment Of Obesity. Interventions: Semaglutide; Berobenatide; Tirzepatide", "status": "Recruiting", "fields": { "phase": "Phase 3", "sponsor": "Pfizer", "enrollment": "660", "nctId": "NCT07845500" }, "jurisdiction": null, "date": "2026-11-05T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07845500", "url": "https://clinicaltrials.gov/study/NCT07845500", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:08.933Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:09.556Z", "change": { "note": "Status changed from “Not yet recruiting” to “Recruiting”", "at": "2026-10-15T14:35:04.243Z", "withinLast7Days": false }, "origin": "automated" }, { "key": "trial:NCT07303322", "record": "MINORA-WOMEN: Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of N1087 in Participants With Female Pattern Hair Loss (MINORA-WOMEN)", "subtitle": "NCT07303322", "detail": "Conditions: Female Pattern Hair Loss; Female Pattern Hair Loss, Androgenic Alopecia. Interventions: N1087; Placebo", "status": "Not yet recruiting", "fields": { "phase": "Phase 3", "sponsor": "Eurofarma Laboratorios S.A.", "enrollment": "372", "nctId": "NCT07303322" }, "jurisdiction": null, "date": "2026-11-04T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07303322", "url": "https://clinicaltrials.gov/study/NCT07303322", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:02.230Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:02.527Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07916740", "record": "Autologous Hair Follicle-Derived Secretome and Platelet-Rich Plasma for Premature Ovarian Insufficiency", "subtitle": "NCT07916740", "detail": "Conditions: Premature Ovarian Insufficiency; POI; Primary Ovarian Insufficiency (Poi); Premature Ovarian Failure (POF). Interventions: Autologous Hair Follicle-Derived Secretome Combined With Platelet-Rich Plasma", "status": "Recruiting", "fields": { "phase": "Phase 2", "sponsor": "Trio Fertility", "enrollment": "15", "nctId": "NCT07916740" }, "jurisdiction": null, "date": "2026-11-04T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07916740", "url": "https://clinicaltrials.gov/study/NCT07916740", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:01.444Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:01.986Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06857942", "record": "A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)", "subtitle": "NCT06857942", "detail": "Conditions: Psoriasis; Overweight or Obesity. Interventions: Tirzepatide", "status": "Recruiting", "fields": { "phase": "Phase 4", "sponsor": "Eli Lilly and Company", "enrollment": "200", "nctId": "NCT06857942" }, "jurisdiction": null, "date": "2026-11-04T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06857942", "url": "https://clinicaltrials.gov/study/NCT06857942", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:08.933Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:09.681Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07806838", "record": "Effects of Dietary Supplements on Muscle Mass and Function While Using GLP-1 Medication", "subtitle": "NCT07806838", "detail": "Conditions: Obesity & Overweight; Muscle Mass and Strength; Muscle Function. Interventions: Whey Protein Supplementation; Maltodextrin Placebo Capsules; Mixed Spice Capsules", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "University of California, Los Angeles", "enrollment": "75", "nctId": "NCT07806838" }, "jurisdiction": null, "date": "2026-11-04T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07806838", "url": "https://clinicaltrials.gov/study/NCT07806838", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-06T13:35:06.284Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-06T13:35:07.328Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07915609", "record": "A Study to Learn About Berobenatide Given Once Weekly in Adults With Knee Osteoarthritis and Overweight or Obesity With or Without Type 2 Diabetes (VESPER-OA 2)", "subtitle": "NCT07915609", "detail": "Conditions: Obesity; Overweight and/or Obesity; Knee Osteoarthritis; Diabetes Melliuts, Type 2. Interventions: Berobenatide; Placebo", "status": "Recruiting", "fields": { "phase": "Phase 3", "sponsor": "Pfizer", "enrollment": "756", "nctId": "NCT07915609" }, "jurisdiction": null, "date": "2026-11-04T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07915609", "url": "https://clinicaltrials.gov/study/NCT07915609", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-05T13:05:06.094Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-05T13:05:06.398Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07697391", "record": "AI-LIFE-T2D-OB: AI-Assisted Lifestyle Intervention Versus Tirzepatide for Obesity and Newly Diagnosed Type 2 Diabetes", "subtitle": "NCT07697391", "detail": "Conditions: Obesity; Diabetes Mellitus, Type 2. Interventions: AI-Assisted Intensive Lifestyle Intervention; Tirzepatide; Standard Lifestyle Management", "status": "Recruiting", "fields": { "phase": "Phase 4", "sponsor": "The First Affiliated Hospital of Anhui Medical University", "enrollment": "285", "nctId": "NCT07697391" }, "jurisdiction": null, "date": "2026-11-04T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07697391", "url": "https://clinicaltrials.gov/study/NCT07697391", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:08.933Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:09.599Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07772960", "record": "SEMA AUD: Semaglutide Dose Effects on Metabolic and Stress Hormone, Craving and Alcohol Use Outcomes", "subtitle": "NCT07772960", "detail": "Conditions: Alcohol Use Disorder (AUD); Obesity (BMI Equal to or >30). Interventions: Placebo; Semaglutide 1.0 mg; Semaglutide 2.0 mg", "status": "Recruiting", "fields": { "phase": "Phase 1", "sponsor": "Yale University", "enrollment": "90", "nctId": "NCT07772960" }, "jurisdiction": null, "date": "2026-11-04T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07772960", "url": "https://clinicaltrials.gov/study/NCT07772960", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-10T04:35:08.468Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-10T04:35:08.953Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07295223", "record": "GALACTUS: Effect of Glp-1 and Antidiabetic sgLT2 Agents for myoCardial infarcTion and Ultrasensitive Inflammatory Surveillance (GALACTUS Trial)", "subtitle": "NCT07295223", "detail": "Conditions: Acute Myocardial Infarction With ST Elevation. Interventions: Dapagliflozin 10 MG Oral Tablet; Semaglutide (Rybelsus®)", "status": "Completed", "fields": { "phase": "Phase 3", "sponsor": "Instituto Mexicano del Seguro Social", "enrollment": "44", "nctId": "NCT07295223" }, "jurisdiction": null, "date": "2026-11-04T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07295223", "url": "https://clinicaltrials.gov/study/NCT07295223", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-10T04:35:08.468Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-10T04:35:08.984Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06975111", "record": "Focusing on the Menopausal Transition to Improve Mid-Life Women's Health", "subtitle": "NCT06975111", "detail": "Conditions: Menopause; Menopause Hot Flashes; Menopause Related Conditions; Cardiovascular. Interventions: Metformin; semaglutide; Anti-hypertensives; Lipid Lowering Medication; Life style intervention; Fezolinetant; Hormonal…", "status": "Recruiting", "fields": { "phase": "Phase 2 / Phase 3", "sponsor": "University of Colorado, Denver", "enrollment": "200", "nctId": "NCT06975111" }, "jurisdiction": null, "date": "2026-11-04T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06975111", "url": "https://clinicaltrials.gov/study/NCT06975111", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-10T04:35:08.468Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-10T04:35:09.047Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07881458", "record": "AMPLIFY-2: A Study of EloraTZP in Adult Participants With Obesity or Overweight and Type 2 Diabetes", "subtitle": "NCT07881458", "detail": "Conditions: Obesity; Overweight; Diabetes Mellitus, Type 2. Interventions: eloralintide and tirzepatide; Tirzepatide", "status": "Recruiting", "fields": { "phase": "Phase 3", "sponsor": "Eli Lilly and Company", "enrollment": "1000", "nctId": "NCT07881458" }, "jurisdiction": null, "date": "2026-11-04T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07881458", "url": "https://clinicaltrials.gov/study/NCT07881458", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:08.933Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:09.640Z", "change": { "note": "Status changed from “Not yet recruiting” to “Recruiting”", "at": "2026-11-04T14:05:05.626Z", "withinLast7Days": false }, "origin": "automated" }, { "key": "trial:NCT05500586", "record": "The Effects of Glucagon on Hepatic Metabolism", "subtitle": "NCT05500586", "detail": "Conditions: Obesity; Type2diabetes; NAFLD. Interventions: Glucagon response study", "status": "Completed", "fields": { "phase": "Phase 1 / Phase 2", "sponsor": "Adrian Vella", "enrollment": "21", "nctId": "NCT05500586" }, "jurisdiction": null, "date": "2026-11-04T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT05500586", "url": "https://clinicaltrials.gov/study/NCT05500586", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-05T13:05:06.094Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-05T13:05:06.156Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06897475", "record": "A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide", "subtitle": "NCT06897475", "detail": "Conditions: Type 2 Diabetes. 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Interventions: The designed physiotherapy program; The Botulinum toxin injection; Task oriented training; Constrained induced movement…", "status": "Completed", "fields": { "phase": "Not applicable", "sponsor": "Cairo University", "enrollment": "51", "nctId": "NCT07057050" }, "jurisdiction": null, "date": "2026-11-03T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07057050", "url": "https://clinicaltrials.gov/study/NCT07057050", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:01.444Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:02.099Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07881432", "record": "AMPLIFY-1: A Study of EloraTZP in Adult Participants With Obesity Without Type 2 Diabetes", "subtitle": "NCT07881432", "detail": "Conditions: Obesity. 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Interventions: DA-005; Topical minoxidil 5%; DA-002; Placebo Oral Tablet; Placebo Topical Solution", "status": "Withdrawn", "fields": { "phase": "Phase 3", "sponsor": "Applied Biology, Inc.", "enrollment": null, "nctId": "NCT06501924" }, "jurisdiction": null, "date": "2026-11-02T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06501924", "url": "https://clinicaltrials.gov/study/NCT06501924", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:02.230Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:02.603Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07909109", "record": "An Open Label Pilot Study Assessing the Impact of Chromium Picolinate Supplementation on Appetite and Cravings in Overweight Individuals", "subtitle": "NCT07909109", "detail": "Conditions: Overweight (BMI > 25); Appetite; Craving. Interventions: Study Product", "status": "Recruiting", "fields": { "phase": "Phase not stated", "sponsor": "Nutrition 21, Inc.", "enrollment": "138", "nctId": "NCT07909109" }, "jurisdiction": null, "date": "2026-11-02T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07909109", "url": "https://clinicaltrials.gov/study/NCT07909109", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-04T08:05:04.219Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-04T08:05:04.757Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07908823", "record": "ERCG vs Intensive Lifestyle Intervention for Weight Regain After GLP-1 RA Discontinuation", "subtitle": "NCT07908823", "detail": "Conditions: Obesity & Overweight. 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Interventions: Semaglutide (Wegovy®)", "status": "Not yet recruiting", "fields": { "phase": "Phase 2", "sponsor": "Aarhus University Hospital", "enrollment": "32", "nctId": "NCT07909889" }, "jurisdiction": null, "date": "2026-11-02T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07909889", "url": "https://clinicaltrials.gov/study/NCT07909889", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-06T13:35:13.317Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-06T13:35:14.088Z", "change": null, "origin": "automated" }, { "key": "trial:NCT04916470", "record": "STEP HFpEF DM: Research Study to Look at How Well Semaglutide Works in People Living With Heart Failure, Obesity and Type 2 Diabetes", "subtitle": "NCT04916470", "detail": "Conditions: Heart Failure With Preserved Ejection Fraction (HFpEF) and Diabetes Mellitus, Type 2. 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Interventions: Maridebart cafraglutide", "status": "Recruiting", "fields": { "phase": "Phase 1", "sponsor": "Amgen", "enrollment": "180", "nctId": "NCT07908316" }, "jurisdiction": null, "date": "2026-11-02T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07908316", "url": "https://clinicaltrials.gov/study/NCT07908316", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-05T13:05:06.094Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-05T13:05:06.995Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07911046", "record": "BOLD: Brain and Obesity Longitudinal Development: Neurobiological Mechanisms of Semaglutide Treatment of Adolescent Obesity", "subtitle": "NCT07911046", "detail": "Conditions: Pediatric Obesity; Obesity. Interventions: Semaglutide", "status": "Not yet recruiting", "fields": { "phase": "Phase not stated", "sponsor": "Erin Mauney", "enrollment": "12", "nctId": "NCT07911046" }, "jurisdiction": null, "date": "2026-11-02T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07911046", "url": "https://clinicaltrials.gov/study/NCT07911046", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-09T03:35:10.793Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-09T03:35:11.466Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07840729", "record": "Evaluate the Safety and Tolerability of Multiple Doses of JMT206 Injection in Obese Participants", "subtitle": "NCT07840729", "detail": "Conditions: Valid MeSH Conditiongs. Interventions: JMT206 injection; Semaglutide injection; Placebo injection", "status": "Recruiting", "fields": { "phase": "Phase 1", "sponsor": "Shanghai JMT-Bio Inc.", "enrollment": "90", "nctId": "NCT07840729" }, "jurisdiction": null, "date": "2026-11-02T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07840729", "url": "https://clinicaltrials.gov/study/NCT07840729", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-09T03:35:10.793Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-09T03:35:11.597Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06924320", "record": "A Study of MET233 in Combination With MET097 in Individuals With Obesity or Overweight With or Without Diabetes", "subtitle": "NCT06924320", "detail": "Conditions: Obesity and Obesity-related Medical Conditions. Interventions: MET233 and MET097; Placebo; MET097", "status": "Completed", "fields": { "phase": "Phase 1 / Phase 2", "sponsor": "Pfizer", "enrollment": "201", "nctId": "NCT06924320" }, "jurisdiction": null, "date": "2026-11-02T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06924320", "url": "https://clinicaltrials.gov/study/NCT06924320", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-05T13:05:06.094Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-05T13:05:06.922Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07906041", "record": "Tirzepatide and Organ-specific Biological Aging", "subtitle": "NCT07906041", "detail": "Conditions: Longevity; Preventive Medicine; Biological Ageing. Interventions: Tirzepatide", "status": "Enrolling by invitation", "fields": { "phase": "Phase 2", "sponsor": "Atria Research and Global Health Institute (ARGHI)", "enrollment": "22", "nctId": "NCT07906041" }, "jurisdiction": null, "date": "2026-11-02T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07906041", "url": "https://clinicaltrials.gov/study/NCT07906041", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-12T05:35:13.895Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-12T05:35:14.431Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07907965", "record": "A Study on the Safety and Clinical Efficacy of Guominkang in the Treatment of Diabetic Kidney Disease", "subtitle": "NCT07907965", "detail": "Conditions: Diabetic Kidney Disease (DKD); Type 2 Diabetes; Albuminuria. Interventions: Guominkang Granules; Standard Antihypertensive, Antidiabetic, and Lipid-Lowering Regimen", "status": "Active, not recruiting", "fields": { "phase": "Phase 2", "sponsor": "Beijing University of Chinese Medicine", "enrollment": "15", "nctId": "NCT07907965" }, "jurisdiction": null, "date": "2026-11-02T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07907965", "url": "https://clinicaltrials.gov/study/NCT07907965", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:06.920Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:07.140Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07854886", "record": "Hypothalamic GLP-1 Response in Healthy Weight and Obesity", "subtitle": "NCT07854886", "detail": "Conditions: Obesity; Normal Weight; Glucose Intolerance. Interventions: Gastric glucose; GLP-1(7-36)NH2; Exendin(9-39)NH2; Isoglycemic intravenous glucose infusion", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "University of Copenhagen", "enrollment": "60", "nctId": "NCT07854886" }, "jurisdiction": null, "date": "2026-11-02T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07854886", "url": "https://clinicaltrials.gov/study/NCT07854886", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-04T12:05:05.310Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-04T12:05:05.782Z", "change": { "note": "Status changed from “Not yet recruiting” to “Recruiting”", "at": "2026-11-02T17:05:06.584Z", "withinLast7Days": false }, "origin": "automated" }, { "key": "trial:NCT07846865", "record": "TIRZE-PAP: Tirzepatide Versus Positive Airway Pressure for the Treatment of Obstructive Sleep Apnoea", "subtitle": "NCT07846865", "detail": "Conditions: Sleep Apnoea; Obesity & Overweight; Sleep Apnea Syndrome, Obstructive. Interventions: Continuous Positive Airway Pressure; Tirzepatide", "status": "Not yet recruiting", "fields": { "phase": "Phase 2 / Phase 3", "sponsor": "Woolcock Institute of Medical Research", "enrollment": "256", "nctId": "NCT07846865" }, "jurisdiction": null, "date": "2026-11-02T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07846865", "url": "https://clinicaltrials.gov/study/NCT07846865", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-12T05:35:13.895Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-12T05:35:14.377Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07756580", "record": "A Study to Evaluate Sequential Administration of Injections of AGN-151586 Followed by BOTOX in Adult Participants for Treatment of Glabellar Lines", "subtitle": "NCT07756580", "detail": "Conditions: Glabellar Lines. Interventions: AGN-151586; BOTOX", "status": "Active, not recruiting", "fields": { "phase": "Phase 1", "sponsor": "AbbVie", "enrollment": "143", "nctId": "NCT07756580" }, "jurisdiction": null, "date": "2026-11-02T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07756580", "url": "https://clinicaltrials.gov/study/NCT07756580", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:03.213Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:03.333Z", "change": { "note": "Status changed from “Recruiting” to “Active, not recruiting”", "at": "2026-11-02T22:35:02.987Z", "withinLast7Days": false }, "origin": "automated" }, { "key": "trial:NCT05888922", "record": "Evaluation of Efficacy and Safety of Oral Minoxidil 1 mg in Female Androgenetic Alopecia", "subtitle": "NCT05888922", "detail": "Conditions: Androgenetic Alopecia; Female Pattern Baldness. Interventions: Minoxidil Tablets; Minoxidil Topical; Placebo oral tablet; Vehicle solution", "status": "Active, not recruiting", "fields": { "phase": "Phase 3", "sponsor": "Industrial Farmacéutica Cantabria, S.A.", "enrollment": "520", "nctId": "NCT05888922" }, "jurisdiction": null, "date": "2026-11-02T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT05888922", "url": "https://clinicaltrials.gov/study/NCT05888922", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:02.230Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:02.564Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07906509", "record": "Comparative Study of The Efficacy and Safety of Subcision Combined With Injection of Exosomes Versus Subcision Alone in Treatment of Atrophic Post- Acne Scars.", "subtitle": "NCT07906509", "detail": "Conditions: Acne Scars - Atrophic. Interventions: Subcision plus exosome injection; Subcision", "status": "Completed", "fields": { "phase": "Not applicable", "sponsor": "Tanta University", "enrollment": "20", "nctId": "NCT07906509" }, "jurisdiction": null, "date": "2026-10-30T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07906509", "url": "https://clinicaltrials.gov/study/NCT07906509", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-12T05:35:07.639Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-12T05:35:08.064Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06700538", "record": "A First-In-Human Study of ARO-INHBE in Adults With Obesity With and Without Type 2 Diabetes Mellitus", "subtitle": "NCT06700538", "detail": "Conditions: Obesity. Interventions: ARO-INHBE; Placebo; Tirzepatide", "status": "Active, not recruiting", "fields": { "phase": "Phase 1 / Phase 2", "sponsor": "Arrowhead Pharmaceuticals", "enrollment": "190", "nctId": "NCT06700538" }, "jurisdiction": null, "date": "2026-10-30T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06700538", "url": "https://clinicaltrials.gov/study/NCT06700538", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-10T04:35:07.703Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-10T04:35:08.226Z", "change": { "note": "Status changed from “Recruiting” to “Active, not recruiting”", "at": "2026-10-30T13:35:10.982Z", "withinLast7Days": false }, "origin": "automated" }, { "key": "trial:NCT07850050", "record": "SYNCHRONIZE®-HERA: A Study to Test Whether Survodutide Helps Women Who Are Living With Overweight or Obesity and Are Going Through or Have Finished Menopause, to Lose Weight", "subtitle": "NCT07850050", "detail": "Conditions: Obesity. Interventions: Survodutide; Placebo", "status": "Not yet recruiting", "fields": { "phase": "Phase 3", "sponsor": "Boehringer Ingelheim", "enrollment": "600", "nctId": "NCT07850050" }, "jurisdiction": null, "date": "2026-10-30T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07850050", "url": "https://clinicaltrials.gov/study/NCT07850050", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-04T08:05:04.219Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-04T08:05:05.059Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06774079", "record": "Glucagon-like Peptide-1 Receptor Agonist (GLP-1 RA) and Diet in Inflammatory Bowel Disease (IBD) Patients", "subtitle": "NCT06774079", "detail": "Conditions: Crohn Disease. Interventions: Tirzepatide; Mediterranean diet", "status": "Active, not recruiting", "fields": { "phase": "Phase 4", "sponsor": "University of Miami", "enrollment": "24", "nctId": "NCT06774079" }, "jurisdiction": null, "date": "2026-10-29T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06774079", "url": "https://clinicaltrials.gov/study/NCT06774079", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-10T04:35:07.703Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-10T04:35:08.294Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07758231", "record": "TAP: Impact of GLP-1 Receptor Agonist Therapy on Alcohol Pharmacokinetics", "subtitle": "NCT07758231", "detail": "Conditions: GLP-1; Alcohol. Interventions: Acute Ethanol Dose", "status": "Not yet recruiting", "fields": { "phase": "Phase 1", "sponsor": "University of Wisconsin, Madison", "enrollment": "5", "nctId": "NCT07758231" }, "jurisdiction": null, "date": "2026-10-29T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07758231", "url": "https://clinicaltrials.gov/study/NCT07758231", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-10T04:35:07.703Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-10T04:35:08.259Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06431308", "record": "Nutritional Therapy to Incretin-based Anti-obesity Medications in the Management of Gastrointestinal Adverse Events", "subtitle": "NCT06431308", "detail": "Conditions: Obesity; Drug. Interventions: nutritional intervention", "status": "Completed", "fields": { "phase": "Not applicable", "sponsor": "Ariel University", "enrollment": "120", "nctId": "NCT06431308" }, "jurisdiction": null, "date": "2026-10-29T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06431308", "url": "https://clinicaltrials.gov/study/NCT06431308", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-06T13:35:13.317Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-06T13:35:14.136Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06299800", "record": "TCPT2023: Phenotyping Patients With Type 2 Diabetes Mellitus and Cancer", "subtitle": "NCT06299800", "detail": "Conditions: Diabetes Mellitus, Type 2; Cancer. Interventions: phenotyping of patients followed at a third-level diabetes centre with cancer", "status": "Recruiting", "fields": { "phase": "Phase not stated", "sponsor": "Azienda Ospedaliero Universitaria Maggiore della Carita", "enrollment": "779", "nctId": "NCT06299800" }, "jurisdiction": null, "date": "2026-10-29T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06299800", "url": "https://clinicaltrials.gov/study/NCT06299800", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-04T12:05:05.310Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-04T12:05:06.069Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07693608", "record": "TRI-MR: An Open-Label Tirzepatide Trial for Comorbid Obesity and Stimulant Use Disorder", "subtitle": "NCT07693608", "detail": "Conditions: Obesity; Methamphetamine Use Disorder; Cocaine Use Disorder; Stimulant Use Disorders. Interventions: Tirzepatide", "status": "Active, not recruiting", "fields": { "phase": "Phase 2", "sponsor": "University of Texas Southwestern Medical Center", "enrollment": "45", "nctId": "NCT07693608" }, "jurisdiction": null, "date": "2026-10-29T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07693608", "url": "https://clinicaltrials.gov/study/NCT07693608", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-10T04:35:07.703Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-10T04:35:08.330Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07728318", "record": "Efficacy, Safety, and Treatment Satisfaction of Once-Weekly Tirzepatide in Obese Type 2 Diabetic Patients", "subtitle": "NCT07728318", "detail": "Conditions: Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight. Interventions: Tirzepatide + Standard Therapy (Intervention Group); Standard Oral Antidiabetic Drugs (OADs)", "status": "Not yet recruiting", "fields": { "phase": "Not applicable", "sponsor": "Akhtar Saeed Medical and Dental College", "enrollment": "52", "nctId": "NCT07728318" }, "jurisdiction": null, "date": "2026-10-29T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07728318", "url": "https://clinicaltrials.gov/study/NCT07728318", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-09T03:35:09.761Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-09T03:35:10.573Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07872904", "record": "FutureShape Family", "subtitle": "NCT07872904", "detail": "Conditions: Obesity; Overweight. Interventions: Family Care; Standard Care; Semaglutide (administered by PDS290 pen-injector); Placebo (administered by PDS290 pen-inje…", "status": "Recruiting", "fields": { "phase": "Phase 4", "sponsor": "Signe Torekov", "enrollment": "400", "nctId": "NCT07872904" }, "jurisdiction": null, "date": "2026-10-29T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07872904", "url": "https://clinicaltrials.gov/study/NCT07872904", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-06T13:35:13.317Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-06T13:35:14.182Z", "change": { "note": "Status changed from “Not yet recruiting” to “Recruiting”", "at": "2026-10-29T18:05:13.865Z", "withinLast7Days": false }, "origin": "automated" }, { "key": "trial:NCT07900438", "record": "A Research Study Looking at Kidney and Heart Health in Adults With Type 2 Diabetes and Chronic Kidney Disease Treated With Semaglutide in China", "subtitle": "NCT07900438", "detail": "Conditions: Cardiovascular Risk; Chronic Kidney Disease. 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Interventions: Botulinum toxin", "status": "Completed", "fields": { "phase": "Not applicable", "sponsor": "Antony Barbosa Institute", "enrollment": "11", "nctId": "NCT07901465" }, "jurisdiction": null, "date": "2026-10-28T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07901465", "url": "https://clinicaltrials.gov/study/NCT07901465", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:03.213Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:03.397Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07901283", "record": "Comparative Analysis of Intralesional Platelet-Rich Plasma, NPH Insulin, and Vitamin C- A New Horizon and Future Hope for Linear Atrophic Scar Management", "subtitle": "NCT07901283", "detail": "Conditions: Linear Atrophic Scars. Interventions: Intradermal injection of autologous platelet rich plasma; Intradermal injection of NPH insulin; Intradermal injection o…", "status": "Completed", "fields": { "phase": "Not applicable", "sponsor": "Aya Ashraf Fouda", "enrollment": "30", "nctId": "NCT07901283" }, "jurisdiction": null, "date": "2026-10-28T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07901283", "url": "https://clinicaltrials.gov/study/NCT07901283", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-10T04:35:01.505Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-10T04:35:02.004Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06456268", "record": "VibraCool Device to Reduce Pain and Opioid Use After Anterior Cruciate Ligament Reconstruction (ACLR)", "subtitle": "NCT06456268", "detail": "Conditions: ACL; Opioid Use; Cryotherapy Effect; Vibration; Exposure; Pain, Postoperative. 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Interventions: Metformin; Ursodeoxycholic Acid", "status": "Terminated", "fields": { "phase": "Phase 4", "sponsor": "King's College London", "enrollment": "55", "nctId": "NCT04407650" }, "jurisdiction": null, "date": "2026-10-28T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT04407650", "url": "https://clinicaltrials.gov/study/NCT04407650", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-03T12:35:06.883Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-03T12:35:07.828Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07900074", "record": "JOULE3: Mechanisms of Weight Loss: Tirzepatide vs Semaglutide", "subtitle": "NCT07900074", "detail": "Conditions: Obesity (Disorder). 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Interventions: Tirzepatide", "status": "Completed", "fields": { "phase": "Phase not stated", "sponsor": "Radboud University Medical Center", "enrollment": "915", "nctId": "NCT07504172" }, "jurisdiction": null, "date": "2026-10-28T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07504172", "url": "https://clinicaltrials.gov/study/NCT07504172", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-09T03:35:09.761Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-09T03:35:10.658Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07075341", "record": "Healthy Living BEYOND Weight Study", "subtitle": "NCT07075341", "detail": "Conditions: Overweight or Obesity. Interventions: None - Observational study", "status": "Recruiting", "fields": { "phase": "Phase not stated", "sponsor": "American Heart Association", "enrollment": "1000000", "nctId": "NCT07075341" }, "jurisdiction": null, "date": "2026-10-28T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07075341", "url": "https://clinicaltrials.gov/study/NCT07075341", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-03T11:05:05.437Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-03T11:05:06.079Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06632444", "record": "LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis", "subtitle": "NCT06632444", "detail": "Conditions: Metabolic Dysfunction Associated Steatohepatitis (MASH); Liver Fibrosis. 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Interventions: SAD IV Dose 1 - 150mg ABS201 IV Single Dose; Placebo IV; ABS-201 SC Multiple Doses; Placebo SC Injection", "status": "Recruiting", "fields": { "phase": "Phase 1 / Phase 2", "sponsor": "Absci Pty Ltd.", "enrollment": "227", "nctId": "NCT07317544" }, "jurisdiction": null, "date": "2026-10-28T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07317544", "url": "https://clinicaltrials.gov/study/NCT07317544", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:02.230Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:02.641Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07819435", "record": "AWAKEN: Phase 2/3 Efficacy and Safety of PP405 in Adult Males", "subtitle": "NCT07819435", "detail": "Conditions: Androgenetic Alopecia. Interventions: PP405 0.05% Topical Gel; Vehicle Topical Gel", "status": "Recruiting", "fields": { "phase": "Phase 2 / Phase 3", "sponsor": "Pelage Pharmaceuticals, Inc.", "enrollment": "600", "nctId": "NCT07819435" }, "jurisdiction": null, "date": "2026-10-28T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07819435", "url": "https://clinicaltrials.gov/study/NCT07819435", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:02.230Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:02.676Z", "change": { "note": "Status changed from “Not yet recruiting” to “Recruiting”", "at": "2026-10-02T22:35:04.717Z", "withinLast7Days": false }, "origin": "automated" }, { "key": "trial:NCT03884075", "record": "Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)", "subtitle": "NCT03884075", "detail": "Conditions: Non-Alcoholic Steatohepatitis; Non-Alcoholic Fatty Liver Disease. 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Interventions: Xtressé Hair Growth Gummies; Placebo Comparator", "status": "Enrolling by invitation", "fields": { "phase": "Not applicable", "sponsor": "Restore Biologics Holdings, Inc. dba Xtressé", "enrollment": "48", "nctId": "NCT07637071" }, "jurisdiction": null, "date": "2026-10-27T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07637071", "url": "https://clinicaltrials.gov/study/NCT07637071", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:02.230Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:02.714Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07626983", "record": "NEUROQUIET: Botulinum Toxin Type A Versus Local Anesthetic Injection for Chronic Neuroma Pain After Combat-Related Amputation", "subtitle": "NCT07626983", "detail": "Conditions: Chronic Pain Due to Injury; Neuroma of Lower Limb; Neural Injury; Neuroma of Upper Limb; Combat Related Symptoms. Interventions: Botulinum Toxin Type A (BoNT-A); Local Anesthetic Solution", "status": "Completed", "fields": { "phase": "Not applicable", "sponsor": "Ukrainian Society of Regional Anesthesia and Pain Therapy", "enrollment": "100", "nctId": "NCT07626983" }, "jurisdiction": null, "date": "2026-10-27T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07626983", "url": "https://clinicaltrials.gov/study/NCT07626983", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-06T13:05:03.718Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-06T13:05:04.579Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07223216", "record": "Study of BMF-650 in Otherwise Healthy Overweight or Obese Adult Participants", "subtitle": "NCT07223216", "detail": "Conditions: Obesity. Interventions: BMF-650", "status": "Completed", "fields": { "phase": "Phase 1", "sponsor": "Biomea Fusion Inc.", "enrollment": "90", "nctId": "NCT07223216" }, "jurisdiction": null, "date": "2026-10-27T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07223216", "url": "https://clinicaltrials.gov/study/NCT07223216", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-02T10:35:05.531Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-02T10:35:06.378Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07221591", "record": "A Study in Healthy People to Compare How 2 Different Formulations of Survodutide Are Taken up by the Body", "subtitle": "NCT07221591", "detail": "Conditions: Healthy. Interventions: survodutide", "status": "Completed", "fields": { "phase": "Phase 1", "sponsor": "Boehringer Ingelheim", "enrollment": "100", "nctId": "NCT07221591" }, "jurisdiction": null, "date": "2026-10-27T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07221591", "url": "https://clinicaltrials.gov/study/NCT07221591", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-02T10:35:05.531Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-02T10:35:06.414Z", "change": null, "origin": "automated" }, { "key": "trial:NCT04019197", "record": "Effects of Semaglutide in HIV-Associated Lipohypertrophy", "subtitle": "NCT04019197", "detail": "Conditions: HIV/AIDS; Lipohypertrophy; Obesity. Interventions: Semaglutide Injectable Product; Placebo", "status": "Completed", "fields": { "phase": "Phase 2", "sponsor": "Case Western Reserve University", "enrollment": "108", "nctId": "NCT04019197" }, "jurisdiction": null, "date": "2026-10-27T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT04019197", "url": "https://clinicaltrials.gov/study/NCT04019197", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-05T13:05:12.219Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-05T13:05:12.943Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07220629", "record": "RESOLVE-2: Study to Explore the Safety and Efficacy of NT-0796 as an Adjunct to Semaglutide in Participants With Obesity (RESOLVE-2)", "subtitle": "NCT07220629", "detail": "Conditions: Obesity. 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Interventions: Liver-expressed antimicrobial peptide 2; Placebo", "status": "Not yet recruiting", "fields": { "phase": "Phase 1 / Phase 2", "sponsor": "University Hospital, Gentofte, Copenhagen", "enrollment": "18", "nctId": "NCT07897383" }, "jurisdiction": null, "date": "2026-10-27T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07897383", "url": "https://clinicaltrials.gov/study/NCT07897383", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-02T10:35:05.531Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-02T10:35:06.480Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07782359", "record": "NSCLC: Impact of Using a GLP1 on Treatment Related Side Effects of Lung Cancer Patients Receiving Lorlatinib", "subtitle": "NCT07782359", "detail": "Conditions: Lung Cancer. 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Interventions: Empagliflozin 25 MG + Liraglutide 1.8 MG; Liraglutide 1.8 MG + Empagliflozin 25 MG", "status": "Completed", "fields": { "phase": "Phase 2", "sponsor": "University Health Network, Toronto", "enrollment": "6", "nctId": "NCT04535960" }, "jurisdiction": null, "date": "2026-10-26T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT04535960", "url": "https://clinicaltrials.gov/study/NCT04535960", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:06.920Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:07.376Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07220382", "record": "PRETOX: Preoperative BOTOX® Injection for Large Ventral Hernia Repair", "subtitle": "NCT07220382", "detail": "Conditions: Hernia Abdominal Wall; Botox Injection; Hernia Incisional Ventral; Hernia Repair With Compartment Syndrome; Hernia Surgery; Hernia; Hernia…. 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Interventions: Intervention A - Electromyography (EMG)-Guided BTX Injection; Intervention B - Endoscopic Catheter BTX Injection", "status": "Not yet recruiting", "fields": { "phase": "Not applicable", "sponsor": "Chinese University of Hong Kong", "enrollment": "17", "nctId": "NCT07894172" }, "jurisdiction": null, "date": "2026-10-26T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07894172", "url": "https://clinicaltrials.gov/study/NCT07894172", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-05T12:35:01.887Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-05T12:35:02.434Z", "change": null, "origin": "automated" }, { "key": "trial:NCT05073835", "record": "BARI-STEP: Semaglutide 2.4 mg in Patients With Poor Weight-loss", "subtitle": "NCT05073835", "detail": "Conditions: Obesity; Diabetes; Metabolic Syndrome. 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Interventions: Olatorepatide; Placebo", "status": "Not yet recruiting", "fields": { "phase": "Phase 3", "sponsor": "Regeneron Pharmaceuticals", "enrollment": "3000", "nctId": "NCT07896265" }, "jurisdiction": null, "date": "2026-10-26T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07896265", "url": "https://clinicaltrials.gov/study/NCT07896265", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-30T07:05:45.278Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-30T07:05:45.888Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07893457", "record": "Effects of Tirzepatide on Esophagogastric Junction Mechanics, Reflux Burden, and Gastric Physiology in Adults With Obesity", "subtitle": "NCT07893457", "detail": "Conditions: Obese Adults. Interventions: Placebo; Tirzepatide", "status": "Not yet recruiting", "fields": { "phase": "Phase 4", "sponsor": "Mayo Clinic", "enrollment": "30", "nctId": "NCT07893457" }, "jurisdiction": null, "date": "2026-10-26T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07893457", "url": "https://clinicaltrials.gov/study/NCT07893457", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-04T12:05:09.561Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-04T12:05:10.113Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06842186", "record": "INLIGHT: A Phase 1/2a Study of WVE-007 in Adults Living With Overweight or Obesity", "subtitle": "NCT06842186", "detail": "Conditions: Overweight and Obesity. Interventions: WVE-007", "status": "Recruiting", "fields": { "phase": "Phase 1 / Phase 2", "sponsor": "Wave Life Sciences USA, Inc.", "enrollment": "400", "nctId": "NCT06842186" }, "jurisdiction": null, "date": "2026-10-26T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06842186", "url": "https://clinicaltrials.gov/study/NCT06842186", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-04T12:05:09.561Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-04T12:05:10.192Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07592546", "record": "THRIVE: Translational Health Research Into Vascular and Neurocognitive Effects of Weight Loss", "subtitle": "NCT07592546", "detail": "Conditions: Class I/II Obesity. 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Interventions: Semaglutide; Placebo", "status": "Recruiting", "fields": { "phase": "Phase 2 / Phase 3", "sponsor": "McGill University Health Centre/Research Institute of the McGill University Health Centre", "enrollment": "40", "nctId": "NCT07891156" }, "jurisdiction": null, "date": "2026-10-23T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07891156", "url": "https://clinicaltrials.gov/study/NCT07891156", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-04T12:05:10.340Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-04T12:05:11.070Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07283978", "record": "RENEW: Real-world Exploration of Digital iNnovation in the Management of Excess Weight", "subtitle": "NCT07283978", "detail": "Conditions: Obesity; Obesity & Overweight. 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Interventions: SYH2082 Injection; Placebo", "status": "Recruiting", "fields": { "phase": "Phase 1", "sponsor": "CSPC ZhongQi Pharmaceutical Technology Co., Ltd.", "enrollment": "60", "nctId": "NCT07532655" }, "jurisdiction": null, "date": "2026-10-23T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07532655", "url": "https://clinicaltrials.gov/study/NCT07532655", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-29T06:35:05.215Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-29T06:35:05.922Z", "change": null, "origin": "automated" }, { "key": "trial:NCT04578652", "record": "Fiber and Metformin Combination Therapy in Adolescents With Severe Obesity and Insulin Resistance", "subtitle": "NCT04578652", "detail": "Conditions: Obesity, Childhood; Insulin Resistance. Interventions: Metformin 850 mg oral tablet bid; Supplemental fiber mixture (35 g total) composed of 6g of Oligofructose + 12g of resi…", "status": "Recruiting", "fields": { "phase": "Phase 3", "sponsor": "University of Alberta", "enrollment": "90", "nctId": "NCT04578652" }, "jurisdiction": null, "date": "2026-10-23T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT04578652", "url": "https://clinicaltrials.gov/study/NCT04578652", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-28T10:35:04.727Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-28T10:35:06.223Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07893106", "record": "A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASC36 Tablets for Oral Use in Adult Participants With Obesity or Overweight", "subtitle": "NCT07893106", "detail": "Conditions: Chronic Weight Management. Interventions: ASC36 tablets, for oral use; ASC36 placebo tablets", "status": "Recruiting", "fields": { "phase": "Phase 1", "sponsor": "Ascletis Pharma (China) Co., Limited", "enrollment": "86", "nctId": "NCT07893106" }, "jurisdiction": null, "date": "2026-10-23T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07893106", "url": "https://clinicaltrials.gov/study/NCT07893106", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:05.068Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:05.319Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07893093", "record": "A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Two Formulations of ASC36 Injection in Participants With Obesity or Overweight", "subtitle": "NCT07893093", "detail": "Conditions: Chronic Weight Management. Interventions: ASC36 Injection A, for subcutaneous use; ASC36 Placebo Injection A, for subcutaneous use; ASC36 Injection B, for subcut…", "status": "Recruiting", "fields": { "phase": "Phase 1", "sponsor": "Ascletis Pharma (China) Co., Limited", "enrollment": "144", "nctId": "NCT07893093" }, "jurisdiction": null, "date": "2026-10-23T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07893093", "url": "https://clinicaltrials.gov/study/NCT07893093", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:05.068Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:05.273Z", "change": null, "origin": "automated" }, { "key": "trial:NCT04324229", "record": "Liragest: Liraglutide in the Prevention of Type 2 Diabetes After Gestational Diabetes", "subtitle": "NCT04324229", "detail": "Conditions: Gestational Diabetes. Interventions: Liraglutide 6 MG/ML [Victoza]; Placebos", "status": "Completed", "fields": { "phase": "Not applicable", "sponsor": "Turku University Hospital", "enrollment": "67", "nctId": "NCT04324229" }, "jurisdiction": null, "date": "2026-10-23T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT04324229", "url": "https://clinicaltrials.gov/study/NCT04324229", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:06.920Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:07.413Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06151964", "record": "CONTEMPO: A Trial to Learn How Safe AZD9550 Monotherapy and Combined With AZD6234 is in People With or Without Type 2 Diabetes Who Are Living With Obesity and Overweight", "subtitle": "NCT06151964", "detail": "Conditions: Overweight and Obesity. Interventions: AZD9550; placebo; AZD9550 and AZD6234", "status": "Active, not recruiting", "fields": { "phase": "Phase 1 / Phase 2", "sponsor": "AstraZeneca", "enrollment": "166", "nctId": "NCT06151964" }, "jurisdiction": null, "date": "2026-10-23T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06151964", "url": "https://clinicaltrials.gov/study/NCT06151964", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-28T10:35:04.727Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-28T10:35:05.931Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07113561", "record": "PRO-FIT: Effects of a High-protein Diet and Resistance Training on Fat-mass Loss Maintenance", "subtitle": "NCT07113561", "detail": "Conditions: Obesity (Body Mass Index >30 kg/m2). Interventions: High-protein diet and resistance training; Balanced control diet", "status": "Active, not recruiting", "fields": { "phase": "Not applicable", "sponsor": "Norwegian University of Science and Technology", "enrollment": "60", "nctId": "NCT07113561" }, "jurisdiction": null, "date": "2026-10-23T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07113561", "url": "https://clinicaltrials.gov/study/NCT07113561", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-28T10:35:04.727Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-28T10:35:06.387Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07893067", "record": "Efficacy and Safety of Triple-Combination Cream Plus Microneedling Along With Tranexamic Acid Versus Platelet-Rich Plasma in the Treatment of Moderate-to-Severe Melasma: A Randomized Comparative Study", "subtitle": "NCT07893067", "detail": "Conditions: Melasma (Facial Melasma). Interventions: Group B (Triple Combination Cream + Microneedling + Platelet-Rich Plasma)", "status": "Active, not recruiting", "fields": { "phase": "Phase 4", "sponsor": "Bangladesh Medical University", "enrollment": "60", "nctId": "NCT07893067" }, "jurisdiction": null, "date": "2026-10-23T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07893067", "url": "https://clinicaltrials.gov/study/NCT07893067", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-05T12:35:01.887Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-05T12:35:02.506Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07225829", "record": "INFLAM MOTION: A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and Osteoarthritis", "subtitle": "NCT07225829", "detail": "Conditions: Knee Osteoarthritis; Synovitis of Knee. Interventions: 4P004; Placebo (NaCl 0.9%)", "status": "Completed", "fields": { "phase": "Phase 2", "sponsor": "4Moving Biotech", "enrollment": "130", "nctId": "NCT07225829" }, "jurisdiction": null, "date": "2026-10-23T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07225829", "url": "https://clinicaltrials.gov/study/NCT07225829", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:06.920Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:07.458Z", "change": { "note": "Status changed from “Active, not recruiting” to “Completed”", "at": "2026-10-23T13:35:10.569Z", "withinLast7Days": false }, "origin": "automated" }, { "key": "trial:NCT04721548", "record": "MINOX: Treatment of Androgenetic Alopecia in Men for 24 Weeks", "subtitle": "NCT04721548", "detail": "Conditions: Alopecia. Interventions: Minoxidil Topical Foam; Placebo", "status": "Completed", "fields": { "phase": "Phase 3", "sponsor": "Eurofarma Laboratorios S.A.", "enrollment": "336", "nctId": "NCT04721548" }, "jurisdiction": null, "date": "2026-10-23T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT04721548", "url": "https://clinicaltrials.gov/study/NCT04721548", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:02.230Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:02.791Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07662213", "record": "Eluminate-2: A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus", "subtitle": "NCT07662213", "detail": "Conditions: Type 2 Diabetes Mellitus. Interventions: Elecoglipron; Semaglutide", "status": "Recruiting", "fields": { "phase": "Phase 3", "sponsor": "AstraZeneca", "enrollment": "1200", "nctId": "NCT07662213" }, "jurisdiction": null, "date": "2026-10-22T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07662213", "url": "https://clinicaltrials.gov/study/NCT07662213", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-03T11:05:10.848Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-03T11:05:11.564Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07889648", "record": "ENI-SPIRE-2: A Clinical Study to Evaluate the Effects of Enicepatide Versus Tirzepatide in Participants With Type 2 Diabetes and Inadequate Blood Sugar Control on Oral Glucose-Lowering Medications", "subtitle": "NCT07889648", "detail": "Conditions: Type 2 Diabetes Mellitus. Interventions: Enicepatide; Tirzepatide", "status": "Not yet recruiting", "fields": { "phase": "Phase 3", "sponsor": "Hoffmann-La Roche", "enrollment": "948", "nctId": "NCT07889648" }, "jurisdiction": null, "date": "2026-10-22T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07889648", "url": "https://clinicaltrials.gov/study/NCT07889648", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-04T12:05:09.561Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-04T12:05:10.225Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07889453", "record": "Switch TZP: Metabolic Effects of Switching From Injectable Semaglutide to Tirzepatide", "subtitle": "NCT07889453", "detail": "Conditions: Obesity; Type 2 Diabetes (T2D). Interventions: Tirzepatide", "status": "Active, not recruiting", "fields": { "phase": "Phase not stated", "sponsor": "LMC Diabetes & Endocrinology Ltd.", "enrollment": "650", "nctId": "NCT07889453" }, "jurisdiction": null, "date": "2026-10-22T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07889453", "url": "https://clinicaltrials.gov/study/NCT07889453", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-03T11:05:10.848Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-03T11:05:11.599Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07058155", "record": "OPTIMAL: Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease", "subtitle": "NCT07058155", "detail": "Conditions: Liver Cirrhoses; Portal Hypertension Related to Cirrhosis; Severe Obesity; TIPS. Interventions: Transjugular Intrahepatic Portosystemic Shunt (TIPS); Sleeve Gastrectomy; Anti-Obesity Pharmacotherapy (Class Effect);…", "status": "Recruiting", "fields": { "phase": "Phase 4", "sponsor": "The Cleveland Clinic", "enrollment": "70", "nctId": "NCT07058155" }, "jurisdiction": null, "date": "2026-10-22T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07058155", "url": "https://clinicaltrials.gov/study/NCT07058155", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-03T11:05:09.871Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-03T11:05:10.600Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07889570", "record": "A Controlled Study to Evaluate the Effects of a Supplement on Weight Loss, Blood Sugar, and Appetite Suppression", "subtitle": "NCT07889570", "detail": "Conditions: Overweight; Obesity; Blood Sugar Regulation; Appetite Suppression; Weight Management. 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Interventions: Focused extracorporeal shockwave therapy", "status": "Recruiting", "fields": { "phase": "Phase 1", "sponsor": "Kessler Foundation", "enrollment": "12", "nctId": "NCT07501429" }, "jurisdiction": null, "date": "2026-10-22T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07501429", "url": "https://clinicaltrials.gov/study/NCT07501429", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-05T12:35:01.887Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-05T12:35:02.537Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07248410", "record": "A Split-Scalp Study Evaluating the Efficacy and Safety of Fractional Laser Therapy With and Without Exosomes in the Treatment of Androgenetic Alopecia", "subtitle": "NCT07248410", "detail": "Conditions: Androgenetic Alopecia. Interventions: fraction laser", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "Chang Gung Memorial Hospital", "enrollment": "30", "nctId": "NCT07248410" }, "jurisdiction": null, "date": "2026-10-22T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07248410", "url": "https://clinicaltrials.gov/study/NCT07248410", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:02.230Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:02.827Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07171723", "record": "SILENCED: Studying the Influence of LEAP2 on Integrated Endocrine Control of Eating During Semaglutide Treatment", "subtitle": "NCT07171723", "detail": "Conditions: Obesity &Amp; Overweight. Interventions: Liver-Expressed Antimicrobial Peptide 2 (LEAP2); Placebo (saline)", "status": "Completed", "fields": { "phase": "Early phase 1", "sponsor": "University Hospital, Gentofte, Copenhagen", "enrollment": "24", "nctId": "NCT07171723" }, "jurisdiction": null, "date": "2026-10-22T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07171723", "url": "https://clinicaltrials.gov/study/NCT07171723", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-02T10:05:11.364Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-02T10:05:11.863Z", "change": null, "origin": "automated" }, { "key": "trial:NCT02977468", "record": "Pembro/IORT: Effects of MK-3475 (Pembrolizumab) on the Breast Tumor Microenvironment in Triple Negative Breast Cancer", "subtitle": "NCT02977468", "detail": "Conditions: Triple Negative Breast Cancer. Interventions: Merck 3475 Pembrolizumab; Intraoperative radiation therapy (IORT)", "status": "Completed", "fields": { "phase": "Phase 1", "sponsor": "Columbia University", "enrollment": "15", "nctId": "NCT02977468" }, "jurisdiction": null, "date": "2026-10-21T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT02977468", "url": "https://clinicaltrials.gov/study/NCT02977468", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-05T12:35:01.887Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-05T12:35:02.609Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07823452", "record": "GUT BOOST: Supplementation of Gut-brain Axis (GLP-1)-Activating Carbohydrates for Increasing Satiety in Adolescents With Obesity", "subtitle": "NCT07823452", "detail": "Conditions: Obesity & Overweight. Interventions: gut-brain axis (GLP-1)-activating food carbohydrate; starch-based placebo control (commercial maltodextrin)", "status": "Not yet recruiting", "fields": { "phase": "Phase 2", "sponsor": "Indiana University", "enrollment": "62", "nctId": "NCT07823452" }, "jurisdiction": null, "date": "2026-10-21T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07823452", "url": "https://clinicaltrials.gov/study/NCT07823452", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-26T07:35:06.557Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-26T07:35:07.270Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06132477", "record": "Impact GLP-1 Agonists Following Bariatric", "subtitle": "NCT06132477", "detail": "Conditions: Morbid Obesity; Metabolic Syndrome; Diabetes Mellitus; Hypertension; Obstructive Sleep Apnea of Adult. 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Interventions: Tirzepatide", "status": "Active, not recruiting", "fields": { "phase": "Early phase 1", "sponsor": "Memorial Sloan Kettering Cancer Center", "enrollment": "4", "nctId": "NCT06751589" }, "jurisdiction": null, "date": "2026-10-21T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06751589", "url": "https://clinicaltrials.gov/study/NCT06751589", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-03T11:05:09.871Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-03T11:05:10.719Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07550816", "record": "Drug-drug Interaction Study of ZT002 Injection in Overweight and Obese Participants", "subtitle": "NCT07550816", "detail": "Conditions: Overweight,Obesity. Interventions: ZT002 injection, metformin, warfarin; ZT002 injection, rosuvastatin, digoxin", "status": "Active, not recruiting", "fields": { "phase": "Phase 1", "sponsor": "Beijing QL Biopharmaceutical Co.,Ltd", "enrollment": "60", "nctId": "NCT07550816" }, "jurisdiction": null, "date": "2026-10-21T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07550816", "url": "https://clinicaltrials.gov/study/NCT07550816", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-27T09:05:07.008Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-27T09:05:08.208Z", "change": null, "origin": "automated" }, { "key": "trial:NCT02275351", "record": "A Study of the Safety, Tolerability, and Efficacy of Topical SM04554 Solution in Male Subjects With Androgenetic Alopecia (AGA)", "subtitle": "NCT02275351", "detail": "Conditions: Androgenetic Alopecia. Interventions: Topical SM04554 solution; Topical SM04554 solution; Topical vehicle solution", "status": "Completed", "fields": { "phase": "Phase 2", "sponsor": "Biosplice Therapeutics, Inc.", "enrollment": "302", "nctId": "NCT02275351" }, "jurisdiction": null, "date": "2026-10-21T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT02275351", "url": "https://clinicaltrials.gov/study/NCT02275351", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:02.230Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:02.912Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07107334", "record": "A Study to Estimate Early Clinical Efficacy Signals of GLP-1 Agonist Administration in Conjunction With Levonorgestrel Intrauterine Device in Obese Patients With Endometrioid Intraepithelial Neoplasia", "subtitle": "NCT07107334", "detail": "Conditions: Endometrioid Endometrial Adenocarcinoma. Interventions: Glucagon-like peptide 1 receptor agonist", "status": "Recruiting", "fields": { "phase": "Phase 2", "sponsor": "University of Florida", "enrollment": "20", "nctId": "NCT07107334" }, "jurisdiction": null, "date": "2026-10-21T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07107334", "url": "https://clinicaltrials.gov/study/NCT07107334", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:06.920Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:07.504Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06393452", "record": "Safety, Pharmacokinetics and Efficacy of PP405 in Adults With AGA", "subtitle": "NCT06393452", "detail": "Conditions: Androgenetic Alopecia. Interventions: PP405 0.05% Topical Gel; Topical Vehicle Gel", "status": "Completed", "fields": { "phase": "Phase 2", "sponsor": "Pelage Pharmaceuticals, Inc.", "enrollment": "78", "nctId": "NCT06393452" }, "jurisdiction": null, "date": "2026-10-21T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06393452", "url": "https://clinicaltrials.gov/study/NCT06393452", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:02.230Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:02.872Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07502508", "record": "Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy", "subtitle": "NCT07502508", "detail": "Conditions: Type 2 Diabetes. Interventions: icovamenib 100 mg; Placebo", "status": "Recruiting", "fields": { "phase": "Phase 2", "sponsor": "Biomea Fusion Inc.", "enrollment": "60", "nctId": "NCT07502508" }, "jurisdiction": null, "date": "2026-10-20T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07502508", "url": "https://clinicaltrials.gov/study/NCT07502508", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-29T06:35:09.275Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-29T06:35:09.869Z", "change": null, "origin": "automated" }, { "key": "trial:NCT04335656", "record": "Reducing Innate Inflammation in New Onset Type 1 Diabetes", "subtitle": "NCT04335656", "detail": "Conditions: Type 1 Diabetes; type1diabetes; Type 1 Diabetes Mellitus. Interventions: Lactiplantibacillus plantarum; Placebo", "status": "Active, not recruiting", "fields": { "phase": "Phase 2", "sponsor": "Medical College of Wisconsin", "enrollment": "51", "nctId": "NCT04335656" }, "jurisdiction": null, "date": "2026-10-20T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT04335656", "url": "https://clinicaltrials.gov/study/NCT04335656", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:05.068Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:05.363Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07881926", "record": "CIP-02-25: Evaluation of MD60002 Device for Facial Skin Aging", "subtitle": "NCT07881926", "detail": "Conditions: Facial Wrinkles; Skin Aging; Skin Imperfections. Interventions: Device: MD60002", "status": "Not yet recruiting", "fields": { "phase": "Not applicable", "sponsor": "Promoitalia Group Spa", "enrollment": "43", "nctId": "NCT07881926" }, "jurisdiction": null, "date": "2026-10-20T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07881926", "url": "https://clinicaltrials.gov/study/NCT07881926", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-05T12:35:01.887Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-05T12:35:02.639Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07820774", "record": "Multimodal Intervention for Weight Management and Health in the Elderly Population", "subtitle": "NCT07820774", "detail": "Conditions: Obesity & Overweight. Interventions: Nutritional guidance focused on adopting a high-protein diet.; Group Cognitive Behavioral Therapy Intervention; Resista…", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "Universidade Cesumar (UNICESUMAR)", "enrollment": "54", "nctId": "NCT07820774" }, "jurisdiction": null, "date": "2026-10-20T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07820774", "url": "https://clinicaltrials.gov/study/NCT07820774", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-23T08:35:02.075Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-23T08:35:02.740Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07574723", "record": "TiTRE: Tirzepatide Titration to Reduce Side Effects in Individuals With Obesity", "subtitle": "NCT07574723", "detail": "Conditions: Obesity. Interventions: Tirzepatide (Per-label titration); Tirzepatide (Flexible titration)", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "Dasman Diabetes Institute", "enrollment": "68", "nctId": "NCT07574723" }, "jurisdiction": null, "date": "2026-10-20T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07574723", "url": "https://clinicaltrials.gov/study/NCT07574723", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-30T07:05:48.817Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-30T07:05:49.323Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07777575", "record": "RESIST: Resistance Training to Prevent Muscle Loss During Treatment With Tirzepatide", "subtitle": "NCT07777575", "detail": "Conditions: Obesity (BMI>30). Interventions: Dual GIP/GLP-1 Receptor Agonist Tirzepatide; Resistance Training", "status": "Recruiting", "fields": { "phase": "Phase 4", "sponsor": "Technical University of Munich", "enrollment": "150", "nctId": "NCT07777575" }, "jurisdiction": null, "date": "2026-10-20T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07777575", "url": "https://clinicaltrials.gov/study/NCT07777575", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-02T10:05:10.512Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-02T10:05:11.254Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07884058", "record": "IGOB131 As A GLP-1 Modulator For Metabolic Disorders In Adults With Obesity", "subtitle": "NCT07884058", "detail": "Conditions: Obesity & Overweight. Interventions: IGOB131; Dextrin", "status": "Not yet recruiting", "fields": { "phase": "Phase 2", "sponsor": "University of Yaounde 1", "enrollment": "80", "nctId": "NCT07884058" }, "jurisdiction": null, "date": "2026-10-20T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07884058", "url": "https://clinicaltrials.gov/study/NCT07884058", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-26T07:35:06.557Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-26T07:35:07.417Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07809568", "record": "TRIBUTE-PK: Real-World Outcomes of Tirzepatide in Pakistani Adults With Obesity, Prediabetes, and Type 2 Diabetes", "subtitle": "NCT07809568", "detail": "Conditions: Prediabetes or Overweight; Obesity Type 2 Diabetes Mellitus; Obesity & Overweight", "status": "Not yet recruiting", "fields": { "phase": "Phase not stated", "sponsor": "Universiti Sains Malaysia", "enrollment": "330", "nctId": "NCT07809568" }, "jurisdiction": null, "date": "2026-10-20T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07809568", "url": "https://clinicaltrials.gov/study/NCT07809568", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-30T07:05:48.817Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-30T07:05:49.352Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07654374", "record": "A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)", "subtitle": "NCT07654374", "detail": "Conditions: Obesity; Overweight; Chronic Weight Management; Type2 Diabetes Mellitus. Interventions: aleniglipron; aleniglipron; aleniglipron; Placebo", "status": "Recruiting", "fields": { "phase": "Phase 3", "sponsor": "Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics", "enrollment": "1100", "nctId": "NCT07654374" }, "jurisdiction": null, "date": "2026-10-20T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07654374", "url": "https://clinicaltrials.gov/study/NCT07654374", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-23T08:35:02.075Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-23T08:35:02.766Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07881783", "record": "STAY SEC PsO: A Real-world Study of Treatment Retention and Adherence to Secukinumab in Patients With Plaque Psoriasis (PsO) With or Without Glucagon-like Peptide-1 Receptor Agonist (GLP-1 RA) Co-therapy", "subtitle": "NCT07881783", "detail": "Conditions: Plaque Psoriasis", "status": "Not yet recruiting", "fields": { "phase": "Phase not stated", "sponsor": "Novartis Pharmaceuticals", "enrollment": "3718", "nctId": "NCT07881783" }, "jurisdiction": null, "date": "2026-10-20T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07881783", "url": "https://clinicaltrials.gov/study/NCT07881783", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:06.920Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:07.557Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07874828", "record": "PROACT AYA: Preventing Overweight/Obesity-Associated Cardiotoxicity With Tirzepatide In Adolescent And Young Adult Cancer Survivors - A Phase 2 Single-Arm, Single-Center Feasibility Study", "subtitle": "NCT07874828", "detail": "Conditions: Sarcoma,Soft Tissue. Interventions: Tirzepatide", "status": "Recruiting", "fields": { "phase": "Phase 2", "sponsor": "M.D. Anderson Cancer Center", "enrollment": "30", "nctId": "NCT07874828" }, "jurisdiction": null, "date": "2026-10-20T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07874828", "url": "https://clinicaltrials.gov/study/NCT07874828", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-02T10:05:10.512Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-02T10:05:11.218Z", "change": { "note": "Status changed from “Not yet recruiting” to “Recruiting”", "at": "2026-10-20T17:35:01.959Z", "withinLast7Days": false }, "origin": "automated" }, { "key": "trial:NCT06977438", "record": "GLOW: GLP-1 Plus Lifestyle for Overall Wellness: Find Your Way Forward", "subtitle": "NCT06977438", "detail": "Conditions: Obesity, Childhood. Interventions: Semaglutide", "status": "Not yet recruiting", "fields": { "phase": "Phase 4", "sponsor": "University of Minnesota", "enrollment": "1020", "nctId": "NCT06977438" }, "jurisdiction": null, "date": "2026-10-20T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06977438", "url": "https://clinicaltrials.gov/study/NCT06977438", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-29T06:35:09.275Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-29T06:35:09.843Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07879612", "record": "S-CUD: Semaglutide for the Treatment of Cannabis Use Disorder", "subtitle": "NCT07879612", "detail": "Conditions: Cannabis Use Disorder; Cue-reactivity. Interventions: semaglutide", "status": "Not yet recruiting", "fields": { "phase": "Phase 2", "sponsor": "Massachusetts General Hospital", "enrollment": "40", "nctId": "NCT07879612" }, "jurisdiction": null, "date": "2026-10-19T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07879612", "url": "https://clinicaltrials.gov/study/NCT07879612", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-28T05:35:10.706Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-28T05:35:11.710Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06976619", "record": "The Effect of Glycemic Control and of GLP-1 Receptor Agonism on Islet GLP-1 in People With Type 1 and Type 2 Diabetes", "subtitle": "NCT06976619", "detail": "Conditions: Type 1 Diabetes; Type 2 Diabetes. Interventions: Liraglutide Pen Injector; Saline Injections", "status": "Recruiting", "fields": { "phase": "Phase 2", "sponsor": "Mayo Clinic", "enrollment": "60", "nctId": "NCT06976619" }, "jurisdiction": null, "date": "2026-10-19T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06976619", "url": "https://clinicaltrials.gov/study/NCT06976619", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:06.920Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:07.598Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06221969", "record": "A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor", "subtitle": "NCT06221969", "detail": "Conditions: Type 2 Diabetes. Interventions: Cagrilintide; Semaglutide; Tirzepatide", "status": "Completed", "fields": { "phase": "Phase 3", "sponsor": "Novo Nordisk A/S", "enrollment": "1024", "nctId": "NCT06221969" }, "jurisdiction": null, "date": "2026-10-19T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06221969", "url": "https://clinicaltrials.gov/study/NCT06221969", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:05.068Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:05.405Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07607587", "record": "Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events", "subtitle": "NCT07607587", "detail": "Conditions: Obesity; Overweight. Interventions: Cagrilintide; Placebo (matched to Cagrilintide)", "status": "Recruiting", "fields": { "phase": "Phase 1", "sponsor": "Novo Nordisk A/S", "enrollment": "114", "nctId": "NCT07607587" }, "jurisdiction": null, "date": "2026-10-19T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07607587", "url": "https://clinicaltrials.gov/study/NCT07607587", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:05.068Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:05.454Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07881770", "record": "SHAPED-AU: Semaglutide Health Outcomes and Patient Adherence in Australia", "subtitle": "NCT07881770", "detail": "Conditions: Overweight; Obesity. Interventions: Semaglutide", "status": "Not yet recruiting", "fields": { "phase": "Phase not stated", "sponsor": "Novo Nordisk A/S", "enrollment": "10000", "nctId": "NCT07881770" }, "jurisdiction": null, "date": "2026-10-19T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07881770", "url": "https://clinicaltrials.gov/study/NCT07881770", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-28T05:35:10.706Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-28T05:35:11.781Z", "change": null, "origin": "automated" }, { "key": "trial:NCT05768958", "record": "TIMEX: Hedonic and Homeostatic Appetite Control in Obesity and Type 2 Diabetes in the Context of Meal and Exercise Timing", "subtitle": "NCT05768958", "detail": "Conditions: Overweight and Obesity; Type 2 Diabetes. Interventions: Exercise; Control", "status": "Completed", "fields": { "phase": "Not applicable", "sponsor": "Steno Diabetes Center Copenhagen", "enrollment": "58", "nctId": "NCT05768958" }, "jurisdiction": null, "date": "2026-10-19T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT05768958", "url": "https://clinicaltrials.gov/study/NCT05768958", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-23T08:35:02.075Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-23T08:35:02.882Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07789106", "record": "Project Zest: A Study on Ubiquinol on Fatigue and Muscle Strength in Healthy Adults Taking GLP-1 Agonists", "subtitle": "NCT07789106", "detail": "Conditions: Obesity & Overweight; GLP - 1; Fatigue Severity Scale; Ubiquinol; Muscle Contraction. Interventions: Ubiquinol 100 MG Oral Capsule; Placebo", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "StudySetGo", "enrollment": "90", "nctId": "NCT07789106" }, "jurisdiction": null, "date": "2026-10-19T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07789106", "url": "https://clinicaltrials.gov/study/NCT07789106", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-22T07:05:02.973Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-22T07:05:03.728Z", "change": null, "origin": "automated" }, { "key": "trial:NCT05378893", "record": "A First in Human (FIH) Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DR10624", "subtitle": "NCT05378893", "detail": "Conditions: Healthy, Obesity, Metabolically. Interventions: DR10624 for injection; Placebo", "status": "Completed", "fields": { "phase": "Phase 1", "sponsor": "Zhejiang Doer Biologics Co., Ltd.", "enrollment": "153", "nctId": "NCT05378893" }, "jurisdiction": null, "date": "2026-10-19T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT05378893", "url": "https://clinicaltrials.gov/study/NCT05378893", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-23T08:35:02.075Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-23T08:35:02.969Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06534411", "record": "REIMAGINE 5: A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or Both", "subtitle": "NCT06534411", "detail": "Conditions: Diabetes Mellitus, Type 2. Interventions: Cagrilintide; Semaglutide; Tirzepatide", "status": "Completed", "fields": { "phase": "Phase 3", "sponsor": "Novo Nordisk A/S", "enrollment": "1023", "nctId": "NCT06534411" }, "jurisdiction": null, "date": "2026-10-19T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06534411", "url": "https://clinicaltrials.gov/study/NCT06534411", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:05.068Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:05.531Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07282613", "record": "REIMAGINEYOUNG: A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes", "subtitle": "NCT07282613", "detail": "Conditions: Diabetes Mellitus, Type 2. Interventions: CagriSema (Cagrilintide B and Semaglutide I); Placebo matched to CagriSema (Cagrilintide B and Semaglutide I)", "status": "Recruiting", "fields": { "phase": "Phase 3", "sponsor": "Novo Nordisk A/S", "enrollment": "80", "nctId": "NCT07282613" }, "jurisdiction": null, "date": "2026-10-19T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07282613", "url": "https://clinicaltrials.gov/study/NCT07282613", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:05.068Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:05.491Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07878494", "record": "Dietary, Medication, and Endoscopic Interventions for Post-Bariatric Hypoglycemia", "subtitle": "NCT07878494", "detail": "Conditions: Post-Bariatric Hypoglycemia. Interventions: Dietary Intervention; GLP-1 receptor agonist or Dual GIP/GLP-1 receptor agonist; Transoral Outlet Reduction (TORe)", "status": "Not yet recruiting", "fields": { "phase": "Not applicable", "sponsor": "Stanford University", "enrollment": "30", "nctId": "NCT07878494" }, "jurisdiction": null, "date": "2026-10-16T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07878494", "url": "https://clinicaltrials.gov/study/NCT07878494", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-27T05:05:10.715Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-27T05:05:11.781Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06192108", "record": "ACHIEVE-2: A Study of Orforglipron (LY3502970) Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin", "subtitle": "NCT06192108", "detail": "Conditions: Type 2 Diabetes. Interventions: Orforglipron; Dapagliflozin", "status": "Completed", "fields": { "phase": "Phase 3", "sponsor": "Eli Lilly and Company", "enrollment": "962", "nctId": "NCT06192108" }, "jurisdiction": null, "date": "2026-10-16T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06192108", "url": "https://clinicaltrials.gov/study/NCT06192108", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:05.987Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:06.319Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07798284", "record": "A Clinical Trial of TQF3250 Capsules in Overweight/Obese Trial Participants With Poor Weight Control Through Simple Lifestyle Intervention", "subtitle": "NCT07798284", "detail": "Conditions: Overweight/Obesity. Interventions: TQF3250 capsules; TQF3250 placebo", "status": "Recruiting", "fields": { "phase": "Phase 1", "sponsor": "Chia Tai Tianqing Pharmaceutical Group Co., Ltd.", "enrollment": "80", "nctId": "NCT07798284" }, "jurisdiction": null, "date": "2026-10-16T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07798284", "url": "https://clinicaltrials.gov/study/NCT07798284", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-21T12:05:07.195Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-21T12:05:08.081Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06715514", "record": "DECLARED-CT: Menopausal Hormone Therapy, GLP-1 Agonists, and Glucose and Energy Homeostasis in Postmenopausal Women With Overweight/Obesity and Impaired Glucose Homeostasis", "subtitle": "NCT06715514", "detail": "Conditions: Menopause; Type 2 Diabetes. Interventions: GLP-1 Receptor Agonist; Menopausal Hormone Therapy", "status": "Active, not recruiting", "fields": { "phase": "Not applicable", "sponsor": "Lia Bally", "enrollment": "96", "nctId": "NCT06715514" }, "jurisdiction": null, "date": "2026-10-16T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06715514", "url": "https://clinicaltrials.gov/study/NCT06715514", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-27T05:05:11.950Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-27T05:05:12.890Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06592261", "record": "GIST: Graded Insulin Suppression Test P&F", "subtitle": "NCT06592261", "detail": "Conditions: Insulin Resistance; Hyperinsulinemia; Obesity; Healthy. Interventions: Insulin regular, 2.0-3.2 mU/m2/min (euinsulinemia); Insulin regular, 32 mU/m2/min (hyperinsulinemia); Octreotide Acetat…", "status": "Completed", "fields": { "phase": "Phase 1", "sponsor": "Columbia University", "enrollment": "20", "nctId": "NCT06592261" }, "jurisdiction": null, "date": "2026-10-16T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06592261", "url": "https://clinicaltrials.gov/study/NCT06592261", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-21T12:05:09.902Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-21T12:05:10.549Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07868835", "record": "Oral VK2735 for Weight Management Phase 3 (SUNRISE 1)", "subtitle": "NCT07868835", "detail": "Conditions: Weight Loss. 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Interventions: ECHO program for DMMC; Usual care", "status": "Enrolling by invitation", "fields": { "phase": "Not applicable", "sponsor": "University of New Mexico", "enrollment": "20", "nctId": "NCT06451458" }, "jurisdiction": null, "date": "2026-10-13T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06451458", "url": "https://clinicaltrials.gov/study/NCT06451458", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-22T00:35:11.845Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-22T00:35:12.492Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07424430", "record": "SEMA-CKM: Real-world Canadian Retrospective Study Evaluating Longitudinal Semaglutide Use on Cardio-Kidney-Metabolic Outcomes", "subtitle": "NCT07424430", "detail": "Conditions: Diabetes (DM); Type 2 Diabetes; Obesity (Disorder). 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Interventions: Tirzepatide; Placebo", "status": "Not yet recruiting", "fields": { "phase": "Phase 2", "sponsor": "Brigham and Women's Hospital", "enrollment": "6", "nctId": "NCT07265752" }, "jurisdiction": null, "date": "2026-10-09T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07265752", "url": "https://clinicaltrials.gov/study/NCT07265752", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-20T11:35:12.715Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-20T11:35:13.564Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07478653", "record": "MODERN-Dental: Pediatric Obesity, Cardiometabolic Risks, And Periodontal Disease", "subtitle": "NCT07478653", "detail": "Conditions: Obesity; Dental Care for Children. Interventions: Dental Cleaning and Oral Hygiene Instruction (OHI); Oral Hygiene Instruction (OHI)", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "Oelisoa Andriankaja", "enrollment": "50", "nctId": "NCT07478653" }, "jurisdiction": null, "date": "2026-10-08T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07478653", "url": "https://clinicaltrials.gov/study/NCT07478653", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-15T08:05:13.817Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-15T08:05:14.632Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07866846", "record": "PasiAcroKeto: Managing Pasireotide-associated Hyperglycaemia in Acromegaly With Ketogenic Diet", "subtitle": "NCT07866846", "detail": "Conditions: Acromegaly Due to Pituitary Adenoma; Hyperglycemia; Ketogenic Diet; Standard Care Control. Interventions: Ketogenic diet; Diabetes Medication", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "Leiden University Medical Center", "enrollment": "30", "nctId": "NCT07866846" }, "jurisdiction": null, "date": "2026-10-08T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07866846", "url": "https://clinicaltrials.gov/study/NCT07866846", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:06.920Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:07.682Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07866183", "record": "TIFFANY: Trial of Innovative Fat-loss Focused Approaches in Patients With Class I Obesity: a Comparative Study", "subtitle": "NCT07866183", "detail": "Conditions: Class I Obesity. Interventions: Tirzepatide; Transcutaneous auricular vagus nerve stimulation", "status": "Recruiting", "fields": { "phase": "Not applicable", "sponsor": "National Medical Research Center for Therapy and Preventive Medicine", "enrollment": "120", "nctId": "NCT07866183" }, "jurisdiction": null, "date": "2026-10-08T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07866183", "url": "https://clinicaltrials.gov/study/NCT07866183", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-19T11:35:10.111Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-19T11:35:10.775Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07858864", "record": "GLP1-SARCO: GLP-1 Receptor Agonist Use and Sarcopenia in Obese Individuals Without Diabetes", "subtitle": "NCT07858864", "detail": "Conditions: Obesity; Sarcopenia. Interventions: GLP-1 receptor agonist (e.g., semaglutide, tirzepatide) - prescribed by the treating physician as standard care; the st…", "status": "Recruiting", "fields": { "phase": "Phase not stated", "sponsor": "Istanbul Saglik Bilimleri University", "enrollment": "42", "nctId": "NCT07858864" }, "jurisdiction": null, "date": "2026-10-08T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07858864", "url": "https://clinicaltrials.gov/study/NCT07858864", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-10-19T11:35:10.111Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-10-19T11:35:10.731Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07165028", "record": "A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)", "subtitle": "NCT07165028", "detail": "Conditions: Metabolic Dysfunction-Associated Steatotic Liver Disease. Interventions: Tirzepatide; Retatrutide; Placebo", "status": "Recruiting", "fields": { "phase": "Phase 3", "sponsor": "Eli Lilly and Company", "enrollment": "4500", "nctId": "NCT07165028" }, "jurisdiction": null, "date": "2026-10-08T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT07165028", "url": "https://clinicaltrials.gov/study/NCT07165028", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:07.948Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:08.154Z", "change": null, "origin": "automated" }, { "key": "trial:NCT06383390", "record": "The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)", "subtitle": "NCT06383390", "detail": "Conditions: Atherosclerotic Cardiovascular Disease (ASCVD); Chronic Kidney Disease (CKD). Interventions: Retatrutide; Placebo", "status": "Active, not recruiting", "fields": { "phase": "Phase 3", "sponsor": "Eli Lilly and Company", "enrollment": "10000", "nctId": "NCT06383390" }, "jurisdiction": null, "date": "2026-10-08T00:00:00.000Z", "dateType": "Last update posted", "source": { "title": "ClinicalTrials.gov record NCT06383390", "url": "https://clinicaltrials.gov/study/NCT06383390", "publisher": "ClinicalTrials.gov (U.S. National Library of Medicine)", "type": "Primary source" }, "lastChecked": "2026-11-15T08:35:07.948Z", "checkedBy": "system", "nphlaUpdatedAt": "2026-11-15T08:35:08.204Z", "change": null, "origin": "automated" }, { "key": "trial:NCT07613307", "record": "ACHIEVE-RAM: A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes Who Observe Ramadan Fasting", "subtitle": "NCT07613307", "detail": "Conditions: Diabetes Mellitus, Type 2; Diabetes Melletus; Glucose Metabolism Disorders; Metabolic Disorders; Nutritional and Metabolic Diseases; Endocr…. 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